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Documento #914
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RNAi gene silencing using cerasome as a viral-size siRNA-carrier free from fusion and cross-linking. Surface-rigidified cerasomes (ceramic-coated liposomes) are neither fused nor cross-linked when bound to siRNA (short duplex RNA) but not to plasmid DNA (long duplex DNA) which induces cross-linking. Non-ceramic reference liposomes are easily fused by the siRNA. The cerasome can thus be used as a viral-size siRNA-carrier in a wide range of concentration for RNAi silencing of exogenous and endogenous genes.
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[-0.06079633, -0.04486876, 0.00015450832, -0.00648801, -0.012344648, ... ]
- Dimensioni 768 dim
- Creato il 31/03/2026 15:19
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