Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1522

MIN ACTIVATION

0.0

Details List

#579 Feature 579

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#187 Feature 187

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#2788 Feature 2788

#2291 Feature 2291

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#2715 Feature 2715

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#362 Feature 362

#463 Feature 463

#1792 Metastatic Cancer

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#2086 Feature 2086

#2857 Feature 2857

#218 Feature 218

#2133 Feature 2133

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#2146 Feature 2146

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#2757 Feature 2757

#2992 Feature 2992

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#770 Feature 770

#1198 Feature 1198

#2999 Feature 2999

#2132 Feature 2132

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#237 Feature 237

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#1481 Feature 1481

#1604 Feature 1604

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#1753 Feature 1753

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#430 Feature 430

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#474 Surgical Procedures & Gastrointestinal Issues

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#231 Feature 231

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#2848 Feature 2848

#515 Feature 515

#777 Feature 777

#1660 Feature 1660

#2451 Feature #2451

#2232 Medical Case Reports & Cancer Research

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#851 Feature 851

#815 Feature 815

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#1202 Feature 1202

#792 Feature 792

#1904 Feature 1904

#1205 Feature 1205

#369 Feature 369

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#234 Feature 234

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#1946 Feature 1946

#1452 Feature 1452

#1896 Feature 1896

#2589 Feature 2589

#766 Feature 766

#1537 Feature 1537

#1210 Feature 1210

#374 Medical Imaging and Oncology

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#290 Feature 290

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#1163 Feature 1163

#1232 Feature 1232

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#1223 Feature 1223

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#2454 Feature 2454

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#3009 Feature 3009

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#1035 Feature 1035

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#416 Feature 416

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#1137 Feature 1137

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#2621 Feature 2621

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#2945 Feature 2945

#3022 Feature 3022

#2749 Feature 2749

#2088 Feature 2088

#2575 Feature 2575

#3023 Feature 3023

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#435 Feature 435

#708 Drug Resistance Mechanisms in Cancer

#1312 Feature 1312

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#982 Feature 982

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#2573 Feature 2573

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#1425 Feature 1425

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#337 Feature 337

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#2622 Feature 2622

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#2130 Feature 2130

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#3064 Surgical Complications and Physiological Stress

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#3070 Spiritual and Holistic Care in Healthcare

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#23 Neuronal Circuitry and Cellular Processes

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#255 Feature 255

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#1908 Feature 1908

#351 Nanomaterial Synthesis and Properties

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Document Content

Hematopoietic stem cell transplantation in chronic lymphocytic leukemia: a report of 12 patients from a single institution.
Stem-cell transplantation is a reasonable therapeutic approach for younger patients with high-risk CLL. Twelve patients (seven males; median age 47 years, range 29-51) with high-risk CLL underwent transplantation (allo, n = 7; auto, n = 5). The conditioning regimen consisted of cyclophosphamide and total body irradiation in 11 patients, and BEAC in the remaining one. Minimal residual disease (MRD) was assessed by cytofluorometry and PCR. All 11 evaluable patients engrafted. Of the seven allografted patients, two died of treatment-related causes; three patients developed acute GVHD. No transplant-related mortality was observed in autografted patients. After transplantation, 10 of 11 patients evaluable for response achieved CR (91%; 95% CI 59%-100%) which was molecular in nine patients (82%; 95% CI 48%-98%). One patient in CR but MRD+ relapsed nine months after transplantation and died. Seven patients remain in molecular CR for a median of 16 months (range 1-58). Estimated actuarial survival and disease-free survival at two years is 81% (95% CI 43%-100%) and 71% (95% CI 43%-99%), respectively. Relapse risk at two years is 12.5% (95% CI 0%-35.5%). Patients with high-risk CLL can achieve long-lasting molecular CR after SCT. The role of transplants in CLL management deserves investigation in controlled trials.

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