Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1575

MIN ACTIVATION

0.0

Details List

#1592 Feature 1592

#2427 Feature 2427

#175 Feature 175

#420 Feature 420

#962 Feature 962

#456 Feature 456

#904 Feature 904

#2406 Feature 2406

#1083 Feature 1083

#2102 Feature 2102

#1743 Feature 1743

#2895 Feature 2895

#2496 Feature 2496

#1720 Feature 1720

#563 Feature 563

#239 Feature 239

#1071 Feature 1071

#1303 Feature 1303

#546 Feature 546

#1308 Feature 1308

#1280 Feature 1280

#750 Feature 750

#534 Feature 534

#1590 Feature 1590

#2274 Feature 2274

#2113 Feature 2113

#798 Feature 798

#2853 Feature 2853

#2151 Feature 2151

#341 Feature 341

#1419 Feature 1419

#1549 Feature 1549

#2682 Feature 2682

#2333 Feature 2333

#1295 Feature 1295

#2033 Feature 2033

#1272 Feature 1272

#2831 Feature 2831

#1674 Feature 1674

#2212 Feature 2212

#479 Feature 479

#1435 Feature 1435

#682 Feature 682

#2188 Feature 2188

#840 Feature 840

#2872 Feature 2872

#342 Feature 342

#892 Feature 892

#458 Feature 458

#1473 Feature 1473

#847 Feature 847

#2497 Feature 2497

#490 Feature 490

#401 Feature 401

#1262 Feature 1262

#1203 Feature 1203

#2191 Feature 2191

#1417 Feature 1417

#2230 Feature 2230

#2357 Feature 2357

#1455 Feature 1455

#1414 Feature 1414

#692 Feature 692

#2555 Feature 2555

#1730 Feature 1730

#1411 Feature 1411

#2304 Feature 2304

#1316 Feature 1316

#1695 Feature 1695

#1194 Feature 1194

#2432 Feature 2432

#617 Feature 617

#2069 Feature 2069

#715 Feature 715

#2471 Feature 2471

#2757 Feature 2757

#2258 Feature 2258

#1210 Feature 1210

#1570 Feature 1570

#2417 Feature 2417

#270 Feature 270

#2549 Feature 2549

#335 Feature 335

#2695 Feature 2695

#517 Feature 517

#2571 Feature 2571

#759 Feature 759

#1546 Feature 1546

#101 Feature 101

#2396 Feature 2396

#1849 Feature 1849

#795 Feature 795

#2481 Feature 2481

#1495 Feature 1495

#1828 Feature 1828

#3042 Feature 3042

#2335 Feature 2335

#2005 Feature 2005

#2215 Feature 2215

#1423 Feature 1423

#2521 Feature 2521

#810 Feature 810

#504 Feature 504

#1359 Feature 1359

#1337 Feature 1337

#503 Feature 503

#1756 Feature 1756

#823 Feature 823

#306 Feature 306

#259 Feature 259

#1794 Feature 1794

#1986 Feature 1986

#1282 Feature 1282

#1994 Feature 1994

#2337 Feature 2337

#2902 Feature 2902

#1374 Feature 1374

#1355 Feature 1355

#2067 Feature 2067

#1840 Feature 1840

#1611 Feature 1611

#402 Feature 402

#3016 Feature 3016

#3021 Feature 3021

#321 Feature 321

#1985 Feature 1985

#1170 Feature 1170

#438 Feature 438

#728 Feature 728

#525 Feature 525

#2372 Feature 2372

#1279 Feature 1279

#1811 Feature 1811

#1467 Feature 1467

#261 Feature 261

#1923 Feature 1923

#1806 Feature 1806

#667 Feature 667

#1557 Feature 1557

#1560 Feature 1560

#1788 Feature 1788

#1191 Feature 1191

#2322 Feature 2322

#1453 Feature 1453

#1072 Feature 1072

#2057 Feature 2057

#964 Feature 964

#1441 Feature 1441

#163 Feature 163

#2342 Feature 2342

#945 Feature 945

#2122 Feature 2122

#2956 Feature 2956

#844 Feature 844

#2823 Feature 2823

#1992 Feature 1992

#1599 Feature 1599

#1620 Feature 1620

#435 Feature 435

#1085 Feature 1085

#170 Feature 170

#2423 Feature 2423

#1628 Feature 1628

#162 Feature 162

#1388 Feature 1388

#2976 Feature 2976

#1143 Feature 1143

#1487 Feature 1487

#2476 Feature 2476

#2152 Feature 2152

#1694 Feature 1694

#482 Feature 482

#411 Feature 411

#2308 Feature 2308

#1930 Feature 1930

#1586 Feature 1586

#303 Feature 303

#1924 Feature 1924

#1667 Feature 1667

#927 Feature 927

#2410 Feature 2410

#600 Feature 600

#564 Feature 564

#23 Neuronal Circuitry and Cellular Processes

#1317 Feature 1317

#833 Feature 833

#2088 Feature 2088

#624 Feature 624

#2325 Feature 2325

#2805 Feature 2805

#2294 Feature 2294

#673 Feature 673

#1392 Feature 1392

#1047 Feature 1047

#1335 Feature 1335

#1358 Feature 1358

#1940 Feature 1940

#1465 Feature 1465

#2970 Feature 2970

#1052 Feature 1052

#100 Feature 100

#1801 Feature 1801

#265 Feature 265

#631 Feature 631

#2381 Feature 2381

#1330 Feature 1330

#2214 Feature 2214

#1186 Feature 1186

#2607 Feature 2607

#2459 Feature 2459

#2801 Feature 2801

#2983 Feature 2983

#1211 Feature 1211

#1309 Feature 1309

#732 Feature 732

#792 Feature 792

#1440 Feature 1440

#364 Feature 364

#130 Feature 130

#2782 Feature 2782

#1065 Feature 1065

#2957 Feature 2957

#464 Feature 464

#2836 Feature 2836

#853 Feature 853

#1537 Feature 1537

#1797 Feature 1797

#2930 Feature 2930

#641 Feature 641

#189 Feature 189

#2791 Feature 2791

#1858 Feature 1858

#2021 Feature 2021

#493 Feature 493

#871 Feature 871

#2749 Feature 2749

#381 Feature 381

#658 Feature 658

#2954 Feature 2954

#2404 Feature 2404

#2564 Feature 2564

#2796 Feature 2796

#539 Feature 539

#2591 Feature 2591

#2436 Feature 2436

#1513 Feature 1513

#688 Feature 688

#2272 Feature 2272

#1651 Feature 1651

#442 Feature 442

#2562 Feature 2562

#1134 Feature 1134

#654 Feature 654

#1878 Feature 1878

#1158 Feature 1158

#2010 Feature 2010

#859 Feature 859

#314 Feature 314

#2309 Feature 2309

#2585 Feature 2585

#1348 Feature 1348

#1895 Feature 1895

#1562 Feature 1562

#1938 Feature 1938

#1486 Feature 1486

#108 Feature 108

#1015 Feature 1015

#2913 Feature 2913

#2397 Feature 2397

#1915 Feature 1915

#1719 Feature 1719

#587 Feature 587

#2992 Feature 2992

#159 Feature 159

#1580 Feature 1580

#3039 Feature 3039

#461 Feature 461

#2552 Feature 2552

#629 Feature 629

#1589 Feature 1589

#2673 Feature 2673

#266 Feature 266

#1515 Feature 1515

#2493 Feature 2493

#2177 Feature 2177

#986 Feature 986

#778 Feature 778

#1872 Feature 1872

#287 Feature 287

#1948 Feature 1948

#419 Feature 419

#672 Feature 672

#1223 Feature 1223

#2491 Feature 2491

#1602 Feature 1602

#2856 Feature 2856

#499 Feature 499

#520 Feature 520

#3002 Feature 3002

#2032 Feature 2032

#1614 Feature 1614

#1155 Feature 1155

#2419 Feature 2419

#1209 Feature 1209

#2718 Feature 2718

#2766 Feature 2766

#243 Feature 243

#2455 Feature 2455

#789 Feature 789

#1983 Feature 1983

#2505 Feature 2505

#1902 Feature 1902

#1519 Feature 1519

#2979 Feature 2979

#492 Feature 492

#2932 Feature 2932

#1903 Feature 1903

#2601 Feature 2601

#389 Feature 389

#537 Feature 537

#3008 Feature 3008

#466 Feature 466

#2200 Feature 2200

#1104 Feature 1104

#2246 Feature 2246

#920 Feature 920

#2996 Feature 2996

#2626 Feature 2626

#476 Feature 476

#693 Feature 693

#191 Feature 191

#1856 Feature 1856

#1825 Feature 1825

#1955 Feature 1955

#1271 Feature 1271

#1403 Feature 1403

#837 Feature 837

#326 Feature 326

#2936 Feature 2936

#2360 Feature 2360

#2201 Feature 2201

#1101 Feature 1101

#1766 Feature 1766

#602 Feature 602

#2905 Feature 2905

#2858 Feature 2858

#1914 Feature 1914

#799 Feature 799

#1629 Feature 1629

#548 Feature 548

#957 Feature 957

#2688 Feature #2688

#522 Feature 522

#2865 Feature 2865

#2252 Feature 2252

#2302 Feature 2302

#749 Feature 749

#1724 Feature 1724

#1229 Feature 1229

#414 Feature 414

#204 Feature 204

#2082 Feature 2082

#264 Feature 264

#496 Feature 496

#2589 Feature 2589

#2944 Feature 2944

#506 Feature 506

#545 Feature 545

#686 Feature 686

#532 Feature 532

#1311 Molecular Mechanisms and Biological Processes

#2661 Feature 2661

#2313 Feature 2313

#430 Feature 430

#828 Feature 828

#2473 Feature 2473

#1770 Feature 1770

#2965 Feature 2965

#583 Feature 583

#190 Feature 190

#1312 Feature 1312

#1098 Feature 1098

#612 Feature 612

#1390 Feature 1390

#278 Feature 278

#555 Feature 555

#211 Feature 211

#2052 Feature 2052

#1307 Feature 1307

#2164 Feature 2164

#1591 Feature 1591

#2071 Feature 2071

#437 Feature 437

#886 Feature 886

#2487 Feature 2487

#2676 Feature 2676

#1615 Feature 1615

#1709 Feature 1709

#1068 Feature 1068

#2863 Feature 2863

#1023 Feature 1023

#1018 Feature 1018

#556 Feature 556

#2854 Feature 2854

#1421 Feature 1421

#2964 Feature 2964

#2195 Feature 2195

#2896 Feature 2896

#1582 Feature 1582

#1060 Feature 1060

#952 Feature 952

#930 Feature 930

#1643 Feature 1643

#614 Feature 614

#923 Feature 923

#205 Feature 205

#1160 Feature 1160

#2908 Feature 2908

#554 Feature 554

#2873 Feature 2873

#373 Feature 373

#198 Feature 198

#369 Feature 369

#1732 Feature 1732

#586 Feature 586

#2120 Feature 2120

#2744 Feature 2744

#1178 Feature 1178

#590 Feature 590

#1514 Feature 1514

#2755 Feature 2755

#1386 Feature 1386

#2229 Feature 2229

#2546 Feature 2546

#1003 Feature 1003

#391 Feature 391

#1816 Feature 1816

#2275 Feature 2275

#1244 Feature 1244

#1844 Feature 1844

#668 Feature 668

#388 Feature 388

#2029 Feature 2029

#1270 Feature 1270

#1253 Feature 1253

#2044 Feature 2044

#1641 Feature 1641

#2429 Feature 2429

#1439 Feature 1439

#2172 Feature 2172

#120 Feature 120

#399 Feature 399

#310 Feature 310

#2572 Feature 2572

#357 Feature 357

#1283 Feature 1283

#2001 Feature 2001

#2002 Feature 2002

#372 Feature 372

#2431 Feature 2431

#2554 Feature 2554

#1618 Feature 1618

#1064 Feature 1064

#687 Feature 687

#2733 Feature 2733

#2207 Feature 2207

#2825 Feature 2825

#2680 Feature 2680

#565 Feature 565

#2221 Feature 2221

#126 Feature 126

#2501 Feature 2501

#2089 Feature 2089

#2812 Feature 2812

#2354 Feature 2354

#1197 Feature 1197

#2756 Feature 2756

#1780 Feature 1780

#296 Feature 296

#2503 Feature 2503

#2446 Feature 2446

#2984 Feature 2984

#1572 Feature 1572

#1081 Feature 1081

#1818 Feature 1818

#147 Feature 147

#2315 Feature 2315

#452 Feature 452

#1202 Feature 1202

#1596 Feature 1596

#1382 Feature 1382

#3009 Feature 3009

#913 Feature 913

#1530 Feature 1530

#2739 Feature 2739

#788 Feature 788

#1942 Feature 1942

#1851 Feature 1851

#758 Feature 758

#1221 Feature 1221

#2468 Feature 2468

#2273 Feature 2273

#557 Feature 557

#1192 Feature 1192

#2400 Feature 2400

#2556 Feature 2556

#2668 Feature 2668

#878 Feature 878

#1215 Feature 1215

#1829 Feature 1829

#2143 Feature 2143

#2269 Feature 2269

#316 Feature 316

#2374 Feature 2374

#855 Feature 855

#494 Feature 494

#1070 Feature 1070

#1764 Feature 1764

#1475 Feature 1475

#1172 Feature 1172

#2742 Feature 2742

#1038 Feature 1038

#413 Feature 413

#790 Feature 790

#2180 Feature 2180

#2480 Feature 2480

#594 Feature 594

#1559 Feature 1559

#2799 Feature 2799

#1109 Feature 1109

#246 Feature 246

#993 Feature 993

#2692 Feature 2692

#2037 Feature 2037

#1479 Feature 1479

#1367 Feature 1367

#2674 Feature 2674

#2059 Feature 2059

#2141 Feature 2141

#1036 Feature 1036

#1057 Feature 1057

#2409 Feature 2409

#1919 Feature 1919

#1277 Feature 1277

#864 Feature 864

#1402 Feature 1402

#1028 Feature 1028

#2169 Feature 2169

#2967 Feature 2967

#1637 Feature 1637

#1241 Feature 1241

#882 Feature 882

#2769 Feature 2769

#2197 Feature 2197

#480 Feature 480

#994 Feature 994

#2613 Feature 2613

#2477 Feature 2477

#1671 Feature 1671

#2185 Feature 2185

#1054 Feature 1054

#1600 Feature 1600

#1126 Feature 1126

#2991 Feature 2991

#2617 Feature 2617

#1078 Feature 1078

#2452 Feature 2452

#1488 Feature 1488

#1833 Feature 1833

#1148 Feature 1148

#1669 Feature 1669

#3023 Feature 3023

#980 Feature 980

#2539 Feature 2539

#2599 Feature 2599

#257 Feature 257

#2383 Feature 2383

#2129 Feature 2129

#1433 Feature 1433

#2517 Feature 2517

#2248 Feature 2248

#1051 Feature 1051

#746 Feature 746

#485 Feature 485

#1758 Feature 1758

#787 Feature 787

#1823 Feature 1823

#1119 Feature 1119

#154 Feature 154

#1792 Metastatic Cancer

#650 Feature 650

#1177 Feature 1177

#1696 Feature 1696

#2767 Feature 2767

#523 Feature 523

#1803 Feature 1803

#1834 Feature 1834

#125 Feature 125

#2157 Feature 2157

#2483 Feature 2483

#2857 Feature 2857

#2877 Feature 2877

#2401 Feature 2401

#2901 Feature 2901

#541 Feature 541

#3057 Feature 3057

#1970 Feature 1970

#739 Feature 739

#2611 Feature 2611

#1242 Feature 1242

#1581 Feature 1581

#1154 Feature 1154

#2462 Feature 2462

#323 Feature 323

#1648 Feature 1648

#394 Feature 394

#1850 Feature 1850

#2134 Feature 2134

#2053 Feature 2053

#143 Feature 143

#912 Feature 912

#1501 Feature 1501

#857 Feature 857

#2235 Feature 2235

#1552 Feature 1552

#1343 Feature 1343

#933 Feature 933

#1369 Feature 1369

#644 Feature 644

#2535 Feature 2535

#2551 Feature 2551

#909 Feature 909

#274 Feature 274

#2382 Feature 2382

#1968 Feature 1968

#2835 Feature 2835

#1086 Feature 1086

#2747 Feature 2747

#2179 Feature 2179

#478 Feature 478

#3026 Feature 3026

#625 Feature 625

#674 Feature 674

#2740 Feature 2740

#1859 Feature 1859

#1332 Feature 1332

#1493 Feature 1493

#2561 Feature 2561

#727 Feature 727

#1778 Feature 1778

#2202 Feature 2202

#1894 Feature 1894

#1551 Feature 1551

#939 Feature 939

#1058 Feature 1058

#967 Feature 967

#1545 Feature 1545

#244 Feature 244

#1962 Feature 1962

#936 Feature 936

#1937 Feature 1937

#2368 Feature 2368

#1947 Feature 1947

#309 Feature 309

#1436 Feature 1436

#1263 Feature 1263

#1226 Feature 1226

#943 Feature 943

#328 Feature 328

#550 Feature 550

#2398 Feature 2398

#1650 Feature 1650

#468 Feature 468

#2630 Feature 2630

#1129 Feature 1129

#1564 Feature 1564

#272 Feature 272

#1616 Feature 1616

#2638 Feature 2638

#2889 Feature 2889

#560 Feature 560

#117 Feature 117

#2300 Feature 2300

#1234 Feature 1234

#2746 Feature 2746

#1624 Feature 1624

#375 Feature 375

#2469 Feature 2469

#184 Feature 184

#1737 Feature 1737

#1255 Feature 1255

#2633 Feature 2633

#445 Feature 445

#1876 Feature 1876

#285 Feature 285

#870 Feature 870

#2762 Feature 2762

#1480 Feature 1480

#2647 Feature 2647

#3014 Feature 3014

#2741 Feature 2741

#731 Feature 731

#1972 Feature 1972

#123 Feature 123

#2012 Feature 2012

#2347 Feature 2347

#3037 Feature 3037

#1306 Feature 1306

#2725 Feature 2725

#974 Feature 974

#2363 Feature 2363

#2995 Feature 2995

#2073 Feature 2073

#3059 Feature 3059

#2948 Feature 2948

#2380 Feature 2380

#1941 Feature 1941

#831 Feature 831

#1452 Feature 1452

#2227 Feature 2227

#2243 Feature 2243

#2980 Feature 2980

#279 Feature 279

#467 Feature 467

#2795 Feature 2795

#2514 Feature 2514

#643 Feature 643

#2118 Feature 2118

#655 Feature 655

#2669 Feature 2669

#410 Feature 410

#3020 Feature 3020

#2464 Feature 2464

#2927 Feature 2927

#2080 Feature 2080

#470 Feature 470

#1812 Feature 1812

#362 Feature 362

#1748 Feature 1748

#1443 Feature 1443

#2536 Feature 2536

#2860 Feature 2860

#505 Feature 505

#2701 Feature 2701

#2679 Feature 2679

#2582 Feature 2582

#2430 Feature 2430

#1408 Feature 1408

#2346 Feature 2346

#2416 Feature 2416

#2909 Feature 2909

#729 Feature 729

#293 Feature 293

#433 Feature 433

#1891 Feature 1891

#1409 Feature 1409

#3005 Feature 3005

#1260 Feature 1260

#2568 Feature 2568

#947 Feature 947

#2850 Feature 2850

#2329 Feature 2329

#2051 Feature 2051

#1432 Feature 1432

#2512 Feature 2512

#2971 Feature 2971

#1543 Feature 1543

#958 Feature 958

#2068 Feature 2068

#1325 Feature 1325

#2189 Feature 2189

#2974 Feature 2974

#579 Feature 579

#1305 Feature 1305

#446 Feature 446

#1693 Feature 1693

#2351 Feature 2351

#2008 Feature 2008

#2096 Feature 2096

#2808 Feature 2808

#1761 Feature 1761

#2962 Feature 2962

#800 Feature 800

#619 Feature 619

#2228 Feature 2228

#1889 Feature 1889

#872 Feature 872

#2317 Feature 2317

#1585 Feature 1585

#2938 Feature 2938

#2448 Feature 2448

#922 Feature 922

#652 Feature 652

#1688 Feature 1688

#1458 Feature 1458

#2236 Feature 2236

#843 Feature 843

#753 Feature 753

#2104 Feature 2104

#116 Feature 116

#1385 Feature 1385

#832 Feature 832

#1594 Feature 1594

#2160 Feature 2160

#1901 Feature 1901

#1161 Feature 1161

#1531 Feature 1531

#1567 Feature 1567

#322 Feature 322

#694 Feature 694

#896 Feature 896

#2660 Feature 2660

#1819 Feature 1819

#2394 Feature 2394

#838 Feature 838

#2224 Feature 2224

#755 Feature 755

#2213 Feature 2213

#1928 Feature 1928

#928 Feature 928

#238 Feature 238

#2283 Feature 2283

#1288 Feature 1288

#2576 Feature 2576

#1494 Feature 1494

#2634 Feature 2634

#1875 Feature 1875

#2717 Feature 2717

#2046 Feature 2046

#959 Feature 959

#2257 Feature 2257

#2377 Feature 2377

#2050 Feature 2050

#2123 Feature 2123

#481 Feature 481

#2349 Feature 2349

#3058 Feature 3058

#2859 Feature 2859

#2545 Feature 2545

#2642 Feature 2642

#2307 Feature 2307

#1837 Feature 1837

#2062 Feature 2062

#1418 Feature 1418

#661 Feature 661

#1426 Feature 1426

#1391 Feature 1391

#229 Feature 229

#2048 Feature 2048

#2341 Feature 2341

#1610 Feature 1610

#796 Feature 796

#817 Feature 817

#971 Feature 971

#784 Feature 784

#3065 Feature 3065

#997 Feature 997

#1094 Feature 1094

#1159 Feature 1159

#950 Feature 950

#2547 Feature 2547

#816 Feature 816

#1394 Feature 1394

#2049 Feature 2049

#1638 Feature 1638

#1681 Feature 1681

#895 Feature 895

#1428 Feature 1428

#706 Feature 706

#307 Feature 307

#2593 Feature 2593

#720 Feature 720

#2999 Feature 2999

#1703 Feature 1703

#2502 Feature 2502

#2016 Feature 2016

#2217 Feature 2217

#2736 Feature 2736

#2713 Feature 2713

#2652 Feature 2652

#2025 Feature 2025

#2874 Feature 2874

#1383 Feature 1383

#1459 Feature 1459

#946 Feature 946

#2358 Feature 2358

#2326 Feature 2326

#2653 Feature 2653

#1676 Feature 1676

#1498 Feature 1498

#979 Feature 979

#1781 Feature 1781

#350 Feature 350

#657 Feature 657

#2119 Feature 2119

#717 Feature 717

#926 Feature 926

#2847 Feature 2847

#711 Feature 711

#1735 Feature 1735

#775 Feature 775

#1153 Feature 1153

#1935 Feature 1935

#1882 Feature 1882

#1470 Feature 1470

#2379 Feature 2379

#2365 Feature 2365

#535 Feature 535

#1754 Feature 1754

#531 Feature 531

#1954 Feature 1954

#2587 Feature 2587

#2225 Feature 2225

#874 Feature 874

#1980 Feature 1980

#1995 Feature 1995

#1002 Feature 1002

#2569 Feature 2569

#2226 Feature 2226

#839 Feature 839

#987 Feature 987

#621 Feature 621

#1759 Feature 1759

#696 Feature 696

#1976 Feature 1976

#1138 Feature 1138

#1338 Feature 1338

#1608 Feature 1608

#1422 Feature 1422

#2532 Feature 2532

#1561 Feature 1561

#1879 Feature 1879

#1354 Feature 1354

#1027 Feature 1027

#1093 Feature 1093

#501 Feature 501

#1700 Feature 1700

#1045 Feature 1045

#712 Feature 712

#791 Feature 791

#386 Feature 386

#2494 Feature 2494

#569 Feature 569

#2271 Feature 2271

#670 Feature 670

#910 Feature 910

#876 Feature 876

#2222 Feature 2222

#2606 Feature 2606

#960 Feature 960

#2301 Feature 2301

#1884 Feature 1884

#985 Feature 985

#1103 Feature 1103

#1297 Feature 1297

#331 Feature 331

#2339 Feature 2339

#1001 Feature 1001

#2735 Feature 2735

#919 Feature 919

#2099 Feature 2099

#1075 Feature 1075

#2148 Feature 2148

#1030 Feature 1030

#1105 Feature 1105

#830 Feature 830

#1997 Feature 1997

#1597 Feature 1597

#2640 Feature 2640

#2612 Feature 2612

#2574 Feature 2574

#1933 Feature 1933

#508 Feature 508

#2754 Feature 2754

#2112 Feature 2112

#1726 Feature 1726

#1235 Feature 1235

#976 Feature 976

#1239 Feature 1239

#3004 Feature 3004

#2711 Feature 2711

#1146 Feature 1146

#620 Feature 620

#156 Feature 156

#252 Feature 252

#195 Feature 195

#2208 Feature 2208

#915 Feature 915

#2055 Feature 2055

#774 Feature 774

#1793 Feature 1793

#1193 Feature 1193

#1491 Feature 1491

#858 Feature 858

#2829 Feature 2829

#1934 Feature 1934

#842 Feature 842

#488 Feature 488

#1568 Feature 1568

#1141 Feature 1141

#595 Feature 595

#2685 Feature 2685

#1949 Feature 1949

#2159 Feature 2159

#577 Feature 577

#2697 Feature 2697

#1167 Feature 1167

#1180 Feature 1180

#905 Feature 905

#529 Feature 529

#2465 Feature 2465

#3011 Feature 3011

#2060 Feature 2060

#1298 Feature 1298

#848 Feature 848

#1401 Feature 1401

#1848 Feature 1848

#794 Feature 794

#3001 Feature 3001

#1079 Feature 1079

#320 Feature 320

#2573 Feature 2573

#1224 Feature 1224

#1691 Feature 1691

#2677 Feature 2677

#2042 Feature 2042

#196 Feature 196

#225 Feature 225

#1009 Feature 1009

#2926 Feature 2926

#1946 Feature 1946

#1046 Feature 1046

#2418 Feature 2418

#1860 Feature 1860

#515 Feature 515

#827 Feature 827

#676 Feature 676

#215 Feature 215

#1037 Feature 1037

#1314 Feature 1314

#628 Feature 628

#849 Feature 849

#1578 Feature 1578

#2170 Feature 2170

#2297 Feature 2297

#2241 Feature 2241

#2966 Feature 2966

#3048 Feature 3048

#3049 Feature 3049

#1740 Feature 1740

#2330 Feature 2330

#961 Feature 961

#902 Feature 902

#2821 Feature 2821

#2319 Feature 2319

#2560 Feature 2560

#741 Feature 741

#570 Feature 570

#2867 Feature 2867

#441 Feature 441

#3045 Feature 3045

#2220 Feature 2220

#102 Feature 102

#2205 Feature 2205

#2482 Feature 2482

#2318 Feature 2318

#2597 Feature 2597

#2074 Feature 2074

#1656 Feature 1656

#2643 Feature 2643

#638 Feature 638

#733 Feature 733

#1716 Feature 1716

#1690 Feature 1690

#148 Feature 148

#2412 Feature 2412

#124 Feature 124

#553 Feature 553

#2542 Feature 2542

#2833 Feature 2833

#544 Feature 544

#2876 Feature 2876

#1137 Feature 1137

#877 Feature 877

#1799 Feature 1799

#2832 Feature 2832

#1744 Feature 1744

#1462 Feature 1462

#2371 Feature 2371

#518 Feature 518

#1087 Feature 1087

#1395 Feature 1395

#2773 Feature 2773

#2299 Feature 2299

#841 Feature 841

#1188 Feature 1188

#635 Feature 635

#2014 Feature 2014

#418 Feature 418

#429 Feature 429

#2199 Feature 2199

#412 Feature 412

#1713 Feature 1713

#459 Feature 459

#1034 Feature 1034

#1662 Feature 1662

#998 Feature 998

#1831 Feature 1831

#2731 Feature 2731

#334 Feature 334

#875 Feature 875

#2479 Feature 2479

#1921 Feature 1921

#2525 Feature 2525

#360 Feature 360

#263 Feature 263

#2609 Feature 2609

#1742 Feature 1742

#685 Feature 685

#1189 Feature 1189

#2703 Feature 2703

#1929 Feature 1929

#1795 Feature 1795

#2281 Feature 2281

#2116 Feature 2116

#144 Feature 144

#1868 Feature 1868

#2378 Feature 2378

#1738 Feature 1738

#2940 Feature 2940

#1147 Feature 1147

#879 Feature 879

#2693 Feature 2693

#2498 Feature 2498

#2007 Developmental Disparities & Intervention

#1053 Feature 1053

#1463 Feature 1463

#2426 Feature 2426

#1555 Feature 1555

#3029 Feature 3029

#1000 Feature 1000

#3068 Feature 3068

#1049 Feature 1049

#1975 Feature 1975

#2066 Feature 2066

#1256 Feature 1256

#2334 Feature 2334

#451 Feature 451

#1679 Feature 1679

#457 Feature 457

#863 Feature 863

#294 Feature 294

#1888 Feature 1888

#2590 Feature 2590

#497 Feature 497

#851 Feature 851

#1577 Feature 1577

#1437 Feature 1437

#1909 Feature 1909

#1634 Feature 1634

#3053 Feature 3053

#2098 Feature 2098

#2941 Feature 2941

#2011 Feature 2011

#1708 Feature 1708

#2659 Feature 2659

#1791 Feature 1791

#114 Feature 114

#2806 Feature 2806

#3025 Feature 3025

#425 Feature 425

#221 Feature 221

#2975 Feature 2975

#2463 Feature 2463

#1905 Feature 1905

#1168 Feature 1168

#1050 Feature 1050

#2293 Feature 2293

#1125 Feature 1125

#2578 Feature 2578

#2035 Feature 2035

#222 Feature 222

#449 Feature 449

#2846 Feature 2846

#2079 Feature 2079

#1299 Feature 1299

#509 Feature 509

#1328 Feature 1328

#1784 Feature 1784

#395 Feature 395

#3032 Feature 3032

#2934 Feature 2934

#2314 Feature 2314

#669 Feature 669

#1556 Feature 1556

#2266 Feature 2266

#250 Feature 250

#1630 Feature 1630

#914 Feature 914

#730 Feature 730

#1302 Sensing and Detection Technologies

#935 Feature 935

#1826 Feature 1826

#2311 Feature 2311

#664 Feature 664

#3060 Feature 3060

#1133 Feature 1133

#209 Feature 209

#2608 Feature 2608

#1266 Feature 1266

#220 Feature 220

#1547 Feature 1547

#345 Feature 345

#1323 Feature 1323

#533 Feature 533

#498 Feature 498

#2022 Feature 2022

#2290 Feature 2290

#1855 Feature 1855

#702 Feature 702

#932 Feature 932

#526 Feature 526

#1431 Feature 1431

#2019 Feature 2019

#2367 Feature 2367

#2655 Feature 2655

#1123 Feature 1123

#1349 Feature 1349

#1817 Feature 1817

#977 Feature 977

#1714 Feature 1714

#2529 Feature 2529

#2277 Feature 2277

#2167 Feature 2167

#1777 Feature 1777

#1925 Feature 1925

#772 Feature 772

#463 Feature 463

#530 Feature 530

#178 Feature 178

#2788 Feature 2788

#822 Feature 822

#735 Feature 735

#513 Feature 513

#2567 Feature 2567

#1623 Feature 1623

#781 Feature 781

#106 Feature 106

#290 Feature 290

#3067 Feature 3067

#1988 Feature 1988

#145 Feature 145

#824 Feature 824

#1363 Feature 1363

#2043 Feature 2043

#2121 Feature 2121

#453 Feature 453

#2784 Feature 2784

#2316 Feature 2316

#1121 Feature 1121

#2878 Feature 2878

#1397 Feature 1397

#2937 Feature 2937

#2892 Feature 2892

#2238 Feature 2238

#1429 Feature 1429

#2826 Feature 2826

#2822 Feature 2822

#2621 Feature 2621

#1464 Feature 1464

#607 Feature 607

#1346 Feature 1346

#2210 Feature 2210

#471 Feature 471

#1963 Feature 1963

#1974 Feature 1974

#1647 Feature 1647

#2624 Feature 2624

#107 Feature 107

#424 Feature 424

#1892 Feature 1892

#540 Feature 540

#115 Feature 115

#2242 Feature 2242

#1959 Feature 1959

#2389 Feature 2389

#2915 Feature 2915

#1377 Feature 1377

#324 Feature 324

#1371 Feature 1371

#3054 Feature 3054

#2678 Feature 2678

#2408 Feature 2408

#1956 Feature 1956

#403 Feature 403

#2667 Feature 2667

#2557 Feature 2557

#1918 Feature 1918

#1646 Feature 1646

#1205 Feature 1205

#1675 Feature 1675

#1529 Feature 1529

#648 Feature 648

#1526 Feature 1526

#2441 Feature 2441

#1366 Feature 1366

#2790 Feature 2790

#1286 Feature 1286

#2961 Feature 2961

#174 Feature 174

#2004 Feature 2004

#1073 Feature 1073

#201 Feature 201

#1438 Feature 1438

#2939 Feature 2939

#2610 Feature 2610

#1274 Feature 1274

#353 Feature 353

#181 Feature 181

#2882 Feature 2882

#965 Feature 965

#1131 Feature 1131

#2910 Feature 2910

#2403 Feature 2403

#1668 Feature 1668

#1542 Feature 1542

#1353 Feature 1353

#642 Feature 642

#2063 Feature 2063

#2843 Feature 2843

#228 Feature 228

#1684 Feature 1684

#1598 Feature 1598

#2061 Feature 2061

#2596 Feature 2596

#2519 Feature 2519

#2486 Feature 2486

#742 Feature 742

#2565 Feature 2565

#382 Feature 382

#803 Feature 803

#472 Feature 472

#2076 Feature 2076

#139 Feature 139

#889 Feature 889

#1653 Feature 1653

#716 Feature 716

#1061 Feature 1061

#633 Feature 633

#1652 Feature 1652

#186 Feature 186

#193 Feature 193

#2087 Feature 2087

#1583 Feature 1583

#1632 Feature 1632

#622 Feature 622

#1575 Feature 1575

#355 Feature 355

#1080 Feature 1080

#1822 Feature 1822

#2875 Feature 2875

#516 Feature 516

#2288 Feature 2288

#1723 Feature 1723

#2516 Feature 2516

#1006 Feature 1006

#2657 Feature 2657

#3043 Feature 3043

#2026 Feature 2026

#1176 Feature 1176

#769 Feature 769

#1832 Feature 1832

#1345 Feature 1345

#319 Feature 319

#1218 Feature 1218

#2947 Feature 2947

#1179 Feature 1179

#1102 Feature 1102

#1245 Feature 1245

#1092 Feature 1092

#1162 Feature 1162

#1534 Feature 1534

#2615 Feature 2615

#2298 Feature 2298

#1768 Feature 1768

#1212 Feature 1212

#2154 Feature 2154

#2841 Feature 2841

#2917 Feature 2917

#2331 Feature 2331

#2387 Feature 2387

#3064 Surgical Complications and Physiological Stress

#981 Feature 981

#317 Feature 317

#1609 Feature 1609

#384 Feature 384

#1163 Feature 1163

#1425 Feature 1425

#133 Feature 133

#512 Feature 512

#2636 Feature 2636

#2714 Feature 2714

#3013 Feature 3013

#2267 Feature 2267

#549 Feature 549

#2171 Molecular and Cellular Biological Processes

#2105 Feature 2105

#230 Feature 230

#2108 Feature 2108

#380 Feature 380

#2028 Feature 2028

#1911 Feature 1911

#820 Feature 820

#992 Feature 992

#2190 Feature 2190

#398 Feature 398

#640 Feature 640

#2538 Feature 2538

#3069 Feature 3069

#1613 Feature 1613

#1228 Feature 1228

#724 Feature 724

#358 Feature 358

#2665 Feature 2665

#113 Feature 113

#2651 Feature 2651

#2869 Feature 2869

#2192 Feature 2192

#804 Feature 804

#182 Feature 182

#1380 Feature 1380

#216 Feature 216

#610 Feature 610

#2715 Feature 2715

#2968 Feature 2968

#1152 Feature 1152

#1019 Feature 1019

#2719 Feature 2719

#2646 Feature 2646

#2499 Feature 2499

#2871 Feature 2871

#868 Feature 868

#1584 Feature 1584

#1612 Feature 1612

#707 Feature 707

#1697 Feature 1697

#346 Feature 346

#1490 Feature 1490

#2466 Feature 2466

#2952 Feature 2952

#1548 Feature 1548

#907 Feature 907

#2145 Feature 2145

#2340 Feature 2340

#1285 Feature 1285

#1654 Feature 1654

#1776 Feature 1776

#2437 Feature 2437

#1504 Feature 1504

#2881 Feature 2881

#1097 Feature 1097

#776 Feature 776

#2135 Feature 2135

#691 Feature 691

#2888 Feature 2888

#2635 Feature 2635

#2985 Feature 2985

#1541 Feature 1541

#1198 Feature 1198

#302 Feature 302

#3019 Feature 3019

#1871 Feature 1871

#649 Feature 649

#404 Interactions and Mechanisms

#576 Feature 576

#1953 Feature 1953

#737 Feature 737

#593 Feature 593

#347 Feature 347

#2837 Feature 2837

#2972 Sensory-Motor Integration

#1601 Feature 1601

#2721 Feature 2721

#2140 Feature 2140

#2391 Feature 2391

#2625 Feature 2625

#361 Feature 361

#2470 Feature 2470

#3024 Feature 3024

#701 Feature 701

#1252 Feature 1252

#2852 Feature 2852

#1739 Feature 1739

#2405 Feature 2405

#2434 Feature 2434

#1678 Feature 1678

#1907 Feature 1907

#2654 Feature 2654

#1067 Feature 1067

#2696 Feature 2696

#608 Feature 608

#2989 Feature 2989

#2440 Feature 2440

#680 Feature 680

#2750 Feature 2750

#289 Feature 289

#2388 Feature 2388

#2818 Feature 2818

#572 Feature 572

#634 Feature 634

#2543 Feature 2543

#1301 Feature 1301

#2994 Feature 2994

#1142 Feature 1142

#1281 Feature 1281

#146 Feature 146

#2249 Feature 2249

#1442 Feature 1442

#122 Feature 122

#1698 Feature 1698

#1124 Feature 1124

#2385 Feature 2385

#584 Feature 584

#2020 Feature 2020

#197 Feature 197

#2687 Feature 2687

#194 Feature 194

#348 Feature 348

#567 Feature 567

#2887 Feature 2887

#1779 Feature 1779

Document Content

Different characteristics distinguish early versus late arising adaptive mutations in Escherichia coli FC40.
The Escherichia coli strain FC40 has frequently been employed to investigate the mechanism of adaptive mutations. The strain cannot utilize lactose due to a +1 frameshift mutation that reduces beta-galactosidase to about 1% of normal levels. Cells undergo a high rate of mutation from Lac- to Lac+ when cells are grown with lactose as the sole energy source. Almost all Lac+ colonies arising 3-6 days after plating result from a base pair deletion in runs of iterated base pairs within a 130-bp target region. In this study we characterized Lac+ colonies arising 3-10 days after plating. Temperature gradient gel electrophoresis (TGGE) was used to detect mutations in the target region as a function of the day a colony appears. TGGE results confirmed the occurrence of mutations within the target region in 36 of 37 FC40 Lac+ colonies arising on days 3-7. However, mutations in this region were not detected in 23 of 37 Lac+ colonies arising from days 8-10. Sequencing data verified the TGGE results. Half of the Lac+ mutants arising on days 8-10 with no base pair change in the target region were unstable and exhibited a Lac- phenotype after successive growth cycles in rich medium. The results suggest that amplification of the lac operon region is a common factor in late arising colonies, and that different characteristics distinguish early and late arising Lac+ colonies.

Similar Documents