Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1506

MIN ACTIVATION

0.0

Details List

#708 Drug Resistance Mechanisms in Cancer

#1087 Feature 1087

#740 Feature 740

#1548 Feature 1548

#887 Feature 887

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#2250 Feature 2250

#1262 Feature 1262

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#1425 Feature 1425

#1671 Feature 1671

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#1965 Feature 1965

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#2421 Feature 2421

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#405 Feature 405

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#2124 Feature 2124

#566 Feature 566

#1722 Feature 1722

#698 Feature 698

#2792 Feature 2792

#1116 Feature 1116

#2848 Feature 2848

#302 Feature 302

#2255 Feature 2255

#1492 Feature 1492

#1058 Feature 1058

#463 Feature 463

#1431 Feature 1431

#1304 Feature 1304

#205 Feature 205

#738 Feature 738

#158 Feature 158

#1476 Feature 1476

#1834 Feature 1834

#2857 Feature 2857

#997 Feature 997

#2914 Feature 2914

#2797 Feature 2797

#3007 Feature 3007

#627 Feature 627

#861 Feature 861

#1496 Feature 1496

#374 Medical Imaging and Oncology

#641 Feature 641

#2419 Feature 2419

#636 Feature 636

#1339 Feature 1339

#1972 Feature 1972

#1237 Feature 1237

#2562 Feature 2562

#558 Feature 558

#1348 Feature 1348

#2803 Feature 2803

#1927 Feature 1927

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#2440 Feature 2440

#1691 Feature 1691

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#548 Feature 548

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#2706 Feature 2706

#2758 Feature 2758

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#1016 Feature 1016

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#2436 Feature 2436

#2050 Feature 2050

#1920 Feature 1920

#1512 Feature 1512

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#115 Feature 115

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#283 Feature 283

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#210 Feature 210

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#2174 Feature 2174

#1802 Feature 1802

#2086 Feature 2086

#422 Feature 422

#868 Feature 868

#1161 Feature 1161

#1994 Feature 1994

#690 Feature 690

#893 Feature 893

#138 Feature 138

#2397 Feature 2397

#2548 Feature 2548

#1701 Feature 1701

#2097 Feature 2097

#1196 Feature 1196

#2800 Feature 2800

#437 Feature 437

#2377 Feature 2377

#430 Feature 430

#661 Feature 661

#892 Feature 892

#2354 Feature 2354

#639 Feature 639

#917 Feature 917

#1392 Feature 1392

#1690 Feature 1690

#1205 Feature 1205

#2125 Feature 2125

#672 Feature 672

#148 Feature 148

#1383 Feature 1383

#1042 Feature 1042

#2658 Feature 2658

#505 Feature 505

#579 Feature 579

#2467 Feature 2467

#701 Feature 701

#268 Feature 268

#2414 Feature 2414

#2997 Feature 2997

#2103 Feature 2103

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#2028 Feature 2028

#2992 Feature 2992

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#2785 Feature 2785

#1996 Feature 1996

#2144 Feature 2144

#1358 Feature 1358

#1569 Feature 1569

#2370 Feature 2370

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#1195 Feature 1195

#2410 Feature 2410

#2709 Feature 2709

#1991 Feature 1991

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#1821 Feature 1821

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#2039 Feature 2039

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#100 Feature 100

#2132 Feature 2132

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#295 Feature 295

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#1861 Feature 1861

#1736 Feature 1736

#1869 Feature 1869

#981 Feature 981

#1925 Feature 1925

#2340 Feature 2340

#1063 Feature 1063

#2671 Feature 2671

#2265 Feature 2265

#1379 Feature 1379

#1539 Feature 1539

#2592 Feature 2592

#941 Feature 941

#1345 Feature 1345

#1044 Feature 1044

#350 Feature 350

#190 Feature 190

#614 Feature 614

#1640 Feature 1640

#386 Feature 386

#1308 Feature 1308

#2907 Feature 2907

#2045 Feature 2045

#2270 Feature 2270

#1436 Feature 1436

#2781 Feature 2781

#1660 Feature 1660

#1184 Feature 1184

#777 Feature 777

#1390 Feature 1390

#427 Feature 427

#635 Feature 635

#191 Feature 191

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#2568 Feature 2568

#2449 Feature 2449

#2790 Feature 2790

#1518 Feature 1518

#2909 Feature 2909

#1118 Feature 1118

#1998 Feature 1998

#1200 Feature 1200

#2589 Feature 2589

#1511 Feature 1511

#3000 Feature 3000

#2610 Feature 2610

#1953 Feature 1953

#835 Feature 835

#686 Feature 686

#1805 Feature 1805

#2802 Feature 2802

#174 Feature 174

#2189 Feature 2189

#1248 Feature 1248

#1700 Feature 1700

#1611 Feature 1611

#1649 Feature 1649

#1369 Feature 1369

#2338 Feature 2338

#1085 Feature 1085

#1645 Feature 1645

#1946 Feature 1946

#1025 Feature 1025

#787 Feature 787

#1929 Feature 1929

#1127 Feature 1127

#885 Feature 885

#2761 Feature 2761

#2481 Feature 2481

#389 Feature 389

#1464 Feature 1464

#282 Feature 282

#264 Feature 264

#3060 Feature 3060

#1448 Feature 1448

#1266 Feature 1266

#2965 Feature 2965

#150 Feature 150

#706 Feature 706

#112 Feature 112

#884 Feature 884

#3039 Feature 3039

#1558 Feature 1558

#1245 Feature 1245

#1572 Feature 1572

#2371 Feature 2371

#2460 Feature 2460

#1625 Feature 1625

#2023 Feature 2023

#2076 Feature 2076

#476 Feature 476

#1731 Feature 1731

#2352 Feature 2352

#2673 Feature 2673

#833 Feature 833

#2576 Feature 2576

#1406 Feature 1406

#2208 Feature 2208

#1475 Feature 1475

#379 Feature 379

#2696 Feature 2696

#2064 Feature 2064

#1393 Feature 1393

#2276 Feature 2276

#783 Feature 783

#2292 Feature 2292

#502 Feature 502

#2152 Feature 2152

#1289 Feature 1289

#2279 Feature 2279

#1292 Feature 1292

#1363 Feature 1363

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#876 Feature 876

#2846 Feature 2846

#1556 Feature 1556

#531 Feature 531

#2495 Feature 2495

#1819 Feature 1819

#1424 Feature 1424

#1644 Feature 1644

#1112 Feature 1112

#235 Feature 235

#2118 Feature 2118

#223 Feature 223

#1452 Feature 1452

#234 Feature 234

#1160 Feature 1160

#2933 Feature 2933

#2368 Feature 2368

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#2638 Feature 2638

#2774 Feature 2774

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#1993 Feature 1993

#555 Feature 555

#1598 Feature 1598

#457 Feature 457

#1473 Feature 1473

#2525 Feature 2525

#2635 Feature 2635

#1961 Feature 1961

#2003 Feature 2003

#2232 Medical Case Reports & Cancer Research

#1137 Feature 1137

#1907 Feature 1907

#447 Feature 447

#2628 Feature 2628

#2829 Feature 2829

#1944 Feature 1944

#1586 Feature 1586

#113 Feature 113

#1530 Feature 1530

#2293 Feature 2293

#362 Feature 362

#1577 Feature 1577

#509 Feature 509

#592 Feature 592

#2600 Feature 2600

#2527 Feature 2527

#1412 Feature 1412

#1328 Feature 1328

#1924 Feature 1924

#419 Feature 419

#110 Feature 110

#1967 Feature 1967

#1897 Feature 1897

#894 Feature 894

#1170 Feature 1170

#890 Feature 890

#2919 Feature 2919

#1218 Feature 1218

#1065 Feature 1065

#2291 Feature 2291

#413 Feature 413

#806 Feature 806

#2437 Feature 2437

#2284 Feature 2284

#493 Feature 493

#618 Feature 618

#2863 Feature 2863

#167 Feature 167

#2160 Feature 2160

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#1404 Feature 1404

#2022 Feature 2022

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#2254 Feature 2254

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#2070 Feature 2070

#1440 Feature 1440

#2828 Feature 2828

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#483 Feature 483

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#2823 Feature 2823

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#2575 Feature 2575

#2165 Feature 2165

#2332 Feature 2332

#273 Feature 273

#1824 Feature 1824

#2201 Feature 2201

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#1329 Feature 1329

#433 Feature 433

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#3023 Feature 3023

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#1192 Feature 1192

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#2599 Feature 2599

#2382 Feature 2382

#1231 Feature 1231

#2336 Feature 2336

#1486 Feature 1486

#1681 Feature 1681

#1964 Feature 1964

#2934 Feature 2934

#2384 Feature 2384

#1816 Feature 1816

#916 Feature 916

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#1455 Feature 1455

#288 Feature 288

#2884 Feature 2884

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#2534 Feature 2534

#1716 Feature 1716

#336 Feature 336

#240 Feature 240

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#2523 Feature 2523

#2718 Feature 2718

#731 Feature 731

#1766 Feature 1766

#2283 Feature 2283

#2403 Feature 2403

#215 Feature 215

#165 Feature 165

#967 Feature 967

#1936 Feature 1936

#582 Feature 582

#2609 Feature 2609

#2788 Feature 2788

#2247 Feature 2247

#514 Feature 514

#2954 Feature 2954

#370 Feature 370

#1843 Feature 1843

#597 Feature 597

#1990 Feature 1990

#1854 Feature 1854

#1238 Feature 1238

#2908 Feature 2908

#2991 Feature 2991

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#3071 Feature 3071

#2871 Feature 2871

#2173 Feature 2173

#2668 Feature 2668

#657 Feature 657

#1560 Feature 1560

#1233 Feature 1233

#2690 Feature 2690

#1910 Feature 1910

#356 Feature 356

#2998 Feature 2998

#1792 Metastatic Cancer

#2002 Feature 2002

#2504 Feature 2504

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#2156 Feature 2156

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#1365 Feature 1365

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#2593 Feature 2593

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#1582 Feature 1582

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#1381 Feature 1381

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#3055 Feature 3055

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#1323 Feature 1323

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#1837 Feature 1837

#1244 Feature 1244

#121 Feature 121

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#1765 Feature 1765

#865 Feature 865

#2903 Feature 2903

#315 Feature 315

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#2821 Feature 2821

#1973 Feature 1973

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#2386 Feature 2386

#1099 Feature 1099

#1784 Feature 1784

#2572 Feature 2572

#1038 Feature 1038

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#2510 Feature 2510

#2652 Feature 2652

#2230 Feature 2230

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#2755 Feature 2755

#600 Feature 600

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#2130 Feature 2130

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#1747 Feature 1747

#2791 Feature 2791

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#1885 Feature 1885

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#2844 Feature 2844

#2337 Feature 2337

#2311 Feature 2311

#2531 Feature 2531

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#1131 Feature 1131

#795 Feature 795

#1595 Feature 1595

#1012 Feature 1012

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#1418 Feature 1418

#475 Feature 475

#815 Feature 815

#2469 Feature 2469

#2583 Feature 2583

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#898 Feature 898

#588 Feature 588

#1483 Feature 1483

#1762 Feature 1762

#1048 Feature 1048

#1702 Feature 1702

#1713 Feature 1713

#2555 Feature 2555

#1000 Feature 1000

#1353 Feature 1353

#2175 Feature 2175

#2155 Feature 2155

#792 Feature 792

#2030 Feature 2030

#238 Feature 238

#1630 Feature 1630

#1285 Feature 1285

#1909 Feature 1909

#2141 Feature 2141

#2127 Feature 2127

#1758 Feature 1758

#1341 Feature 1341

#2426 Feature 2426

#556 Feature 556

#2886 Feature 2886

#1222 Feature 1222

#2809 Feature 2809

#3046 Feature 3046

#1728 Feature 1728

#382 Feature 382

#397 Feature 397

#1106 Feature 1106

#599 Feature 599

#1829 Feature 1829

#2222 Feature 2222

#1223 Feature 1223

#2795 Feature 2795

#2464 Feature 2464

#1398 Feature 1398

#2106 Feature 2106

#1810 Feature 1810

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#194 Feature 194

#2462 Feature #2462

#1399 Feature 1399

#415 Feature 415

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#133 Feature 133

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#2190 Feature 2190

#1839 Feature 1839

#1254 Feature 1254

#1517 Feature 1517

#2100 Feature 2100

#23 Neuronal Circuitry and Cellular Processes

#2985 Feature 2985

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#1319 Feature 1319

#1540 Feature #1540

#242 Feature 242

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#1357 Feature 1357

#2598 Feature 2598

#2063 Feature 2063

#2170 Feature 2170

#1293 Feature 1293

#2126 Feature 2126

#1311 Molecular Mechanisms and Biological Processes

#2804 Feature 2804

#303 Feature 303

#1039 Feature 1039

#1607 Feature 1607

#2040 Feature 2040

#1796 Feature 1796

#2341 Feature 2341

#2318 Feature 2318

#2730 Feature 2730

#768 Feature 768

#1337 Feature 1337

#1703 Feature 1703

#417 Feature #417

#1420 Feature 1420

#1866 Feature 1866

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#2950 Feature 2950

#1828 Feature 1828

#2585 Feature 2585

#1976 Feature 1976

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#766 Feature 766

#250 Feature 250

#2224 Feature 2224

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#1677 Feature 1677

#1786 Feature 1786

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#2298 Feature 2298

#1515 Feature 1515

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#3006 Feature 3006

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#1904 Feature 1904

#102 Feature 102

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#3061 Feature 3061

#557 Feature 557

#879 Feature 879

#1290 Feature 1290

#3070 Spiritual and Holistic Care in Healthcare

#2747 Feature 2747

#1739 Feature 1739

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#2827 Feature 2827

#2136 Feature 2136

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#1162 Feature 1162

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#2326 Feature 2326

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#934 Feature 934

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#1550 Feature 1550

#598 Feature 598

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#745 Feature 745

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#1634 Feature 1634

#254 Feature 254

#1359 Feature 1359

#2470 Feature 2470

#1128 Feature 1128

#114 Feature 114

#1966 Feature 1966

#2021 Feature 2021

#1080 Feature 1080

#1921 Feature 1921

#2171 Molecular and Cellular Biological Processes

#1609 Feature 1609

#1600 Feature 1600

#1240 Feature 1240

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#186 Feature 186

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#416 Feature 416

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#1317 Feature 1317

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#2313 Feature 2313

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#2007 Developmental Disparities & Intervention

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#2972 Sensory-Motor Integration

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#222 Feature 222

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#2260 Historical Context & Development

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#1720 Feature 1720

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#1376 Feature 1376

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Document Content

Methylglyoxal bis(butylamidinohydrazone) exhibits antitumor effect on human malignant melanoma cells but reduces the antitumor action of cisplatin.
The antitumor effect of a polyamine biosynthetic pathway inhibitor methylglyloxal bis(butylamidinohydrazone) (MGBB) on human malignant melanoma (HMG) cells and its combination effect with cisplatin were investigated. The growth of cultured HMG cells was inhibited in a dose dependent manner by either MGBB or cisplatin; complete inhibition of cell proliferation was attained with 5 micrograms/ml of MGBB or 50 micrograms/ml of cisplatin. Pretreatment of HMG cells with MGBB diminished the antitumor action of cisplatin. The cultured HMG cells were inoculated in nude mice and aliquots of the resulting solid tumors (HMG tumor) were transplanted. The growth of transplanted HMG tumors in mice was inhibited markedly by cisplatin (3.8 mg/kg) and moderately by MGBB (10 or 20 mg/kg). The in vivo antitumor effect of cisplatin was also reduced by combined treatment with MGBB.

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