Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1471

MIN ACTIVATION

0.0

Details List

#1749 Feature 1749

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#2073 Feature 2073

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#708 Drug Resistance Mechanisms in Cancer

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#374 Medical Imaging and Oncology

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#23 Neuronal Circuitry and Cellular Processes

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#2161 Medical/Scientific Discourse with Ethical/Social Implications

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#1523 Feature 1523

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#2972 Sensory-Motor Integration

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#2232 Medical Case Reports & Cancer Research

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Document Content

Sequence variation in the src gene product affects metastasis formation: the central, but not exclusive, role of the tumor immune response.
Sequence variation in the src gene product could, in principle, influence metastasis formation through either of 2 effects: an alteration in tumor antigenicity or a non-immune-mediated change in one or more src-associated functions. Our present results establish that both mechanisms underlie the difference in relative levels of metastasis formation induced by the v-src vs. the c-src(527) oncogene. A point that emerges from this analysis is the segregation, within a chicken line genotypically uniform at the major histocompatibility (B) complex (MHC), of a phenotype defined by strong resistance to secondary v-src-induced tumor challenge. The pattern of segregation is consonant with the possibility that a gene unlinked to the MHC governs immune response levels to v-src-encoded tumor antigen.

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