Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1455

MIN ACTIVATION

0.0

Details List

#210 Feature 210

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#273 Feature 273

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#2232 Medical Case Reports & Cancer Research

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#1481 Feature 1481

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#1768 Feature 1768

#2146 Feature 2146

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#1899 Feature 1899

#2255 Feature 2255

#2778 Hippocampal Memory and Cognitive Function

#250 Feature 250

#1660 Feature 1660

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#2914 Feature 2914

#1476 Feature 1476

#1765 Feature 1765

#808 Feature 808

#2134 Feature 2134

#337 Feature 337

#2066 Feature 2066

#2972 Sensory-Motor Integration

#1993 Feature 1993

#622 Feature 622

#1088 Feature 1088

#1134 Feature 1134

#3032 Feature 3032

#2204 Feature 2204

#152 Feature 152

#981 Feature 981

#1403 Feature 1403

#3001 Feature 3001

#2497 Feature 2497

#3064 Surgical Complications and Physiological Stress

#2731 Feature 2731

#2922 Feature 2922

#1991 Feature 1991

#1773 Feature 1773

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#868 Feature 868

#548 Feature 548

#2029 Feature 2029

#118 Feature 118

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#2028 Feature 2028

#1516 Feature 1516

#2351 Feature 2351

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#1539 Feature 1539

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#483 Feature 483

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#580 Feature 580

#1480 Feature 1480

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#420 Feature 420

#2916 Feature 2916

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#510 Feature 510

#1596 Feature 1596

#374 Medical Imaging and Oncology

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#1196 Feature 1196

#2027 Feature 2027

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#1509 Feature 1509

#3040 Feature 3040

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#171 Feature 171

#1914 Feature 1914

#1491 Feature 1491

#1506 Justification/Rationale for Actions

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#670 Feature 670

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#140 Feature 140

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#2510 Feature 2510

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#2132 Feature 2132

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#2930 Feature 2930

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#2060 Feature 2060

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#1210 Feature 1210

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#2626 Feature 2626

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#1520 Feature 1520

#2760 Feature 2760

#556 Feature 556

#1131 Feature 1131

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#1307 Feature 1307

#1266 Feature 1266

#1488 Feature 1488

#1848 Feature 1848

#2372 Feature 2372

#1792 Metastatic Cancer

#790 Feature 790

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#2243 Feature 2243

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#1105 Feature 1105

#2251 Feature 2251

#2623 Feature 2623

#2644 Feature 2644

#1867 Feature 1867

#1941 Feature 1941

#1003 Feature 1003

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#2260 Historical Context & Development

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#1912 Feature 1912

#2647 Feature 2647

#582 Feature 582

#703 Feature 703

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#249 Feature 249

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#415 Feature 415

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#1452 Feature 1452

#2449 Feature 2449

#708 Drug Resistance Mechanisms in Cancer

#2451 Feature #2451

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#1968 Feature 1968

#474 Surgical Procedures & Gastrointestinal Issues

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Document Content

Romidepsin in relapsed/refractory T-cell lymphomas: Italian experience and results of a named patient program.
Clinical trial results indicate that romidepsin, a histone deacetylase inhibitor, is a promising treatment in relapsed/refractory T-cell lymphomas (TCLs). This retrospective multicenter study was conducted in patients with relapsed/refractory TCL treated with romidepsin monotherapy through a Named Patient Program (NPP) in Italy. Principal endpoints were overall response rate (ORR), safety, and overall survival (OS). The ORR in 33 evaluable patients was 24.2% with an ORR in the cutaneous TCL of 35.7%. Global OS was 39.3% at 30 months. There were not any specific differences on hematological and extrahematological adverse events. Data from patients treated with romidepsin outside a controlled clinical trial give additional information about the clinical use, efficacy, and toxicity of the drug given to relapsed or refractory TCL patients in a real life context as TCLs are rare diseases and more information is needed. These findings suggest that romidepsin is effective and safe for heavily pretreated TCL patients.

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