PRISMΔDB

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Active Features

1512

0.0
Details List
#1933 Feature 1933
2.9
#1311 Molecular Mechanisms and Biological Processes
2.6
#1146 Feature 1146
2.5
#2735 Feature 2735
2.4
#52 Feature 52
2.3
#434 Feature 434
2.2
#786 Feature 786
2.2
#2532 Feature 2532
2.2
#410 Feature 410
2.2
#397 Feature 397
2.1
#335 Feature 335
2.1
#592 Feature 592
2.1
#319 Feature 319
2.0
#2054 Feature 2054
1.9
#1930 Feature 1930
1.9
#142 Feature 142
1.8
#496 Feature 496
1.8
#986 Feature 986
1.8
#1863 Feature 1863
1.8
#536 Feature 536
1.8
#1285 Feature 1285
1.7
#2709 Feature 2709
1.7
#1630 Feature 1630
1.7
#152 Feature 152
1.7
#1988 Feature 1988
1.6
#473 Feature 473
1.6
#2388 Feature 2388
1.6
#1917 Feature 1917
1.6
#561 Feature 561
1.5
#160 Feature 160
1.5
#103 Feature 103
1.5
#1244 Feature 1244
1.5
#635 Feature 635
1.4
#1018 Feature 1018
1.4
#86 Feature 86
1.4
#1762 Feature 1762
1.4
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1.4
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1.4
#1324 Feature 1324
1.4
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1.4
#2611 Feature 2611
1.4
#1554 Feature 1554
1.4
#1947 Feature 1947
1.4
#2574 Feature 2574
1.4
#2061 Feature 2061
1.3
#371 Feature 371
1.3
#753 Feature 753
1.3
#2043 Feature 2043
1.3
#170 Feature 170
1.3
#2435 Feature 2435
1.3
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1.3
#903 Feature 903
1.3
#1685 Feature 1685
1.3
#443 Feature 443
1.3
#1525 Feature 1525
1.3
#1595 Feature 1595
1.3
#948 Feature 948
1.3
#864 Feature 864
1.3
#1534 Feature 1534
1.3
#24 Feature 24
1.3
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1.3
#608 Feature 608
1.3
#100 Feature 100
1.3
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1.3
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1.3
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1.3
#1 Feature 1
1.3
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1.3
#751 Feature 751
1.3
#869 Feature 869
1.3
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1.2
#932 Feature 932
1.2
#2102 Feature 2102
1.2
#532 Feature 532
1.2
#2954 Feature 2954
1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
#2022 Feature 2022
1.2
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
#280 Feature 280
1.1
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1.1
#2027 Feature 2027
1.1
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1.1
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1.1
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1.1
#1522 Feature 1522
1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
#1532 Feature 1532
1.1
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1.1
#95 Feature 95
1.1
#2268 Feature 2268
1.1
#2093 Feature 2093
1.1
#11 Feature 11
1.1
#1672 Feature 1672
1.0
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1.0
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1.0
#1565 Feature 1565
1.0
#1003 Feature 1003
1.0
#14 Feature 14
1.0
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1.0
#312 Feature 312
1.0
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1.0
#1487 Feature 1487
1.0
#2100 Feature 2100
1.0
#1717 Feature 1717
1.0
#2540 Feature 2540
1.0
#1804 Feature 1804
1.0
#1273 Feature 1273
1.0
#1110 Feature 1110
1.0
#2696 Feature 2696
1.0
#1919 Feature 1919
1.0
#2062 Feature 2062
1.0
#2177 Feature 2177
1.0
#2369 Feature 2369
1.0
#2853 Feature 2853
1.0
#559 Feature 559
1.0
#1720 Feature 1720
1.0
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1.0
#2198 Feature 2198
1.0
#1916 Feature 1916
1.0
#2169 Feature 2169
1.0
#2634 Feature 2634
1.0
#719 Feature 719
1.0
#457 Feature 457
1.0
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1.0
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1.0
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1.0
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1.0
#695 Feature 695
1.0
#2016 Feature 2016
1.0
#2446 Feature 2446
1.0
#3004 Feature 3004
1.0
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1.0
#3031 Feature 3031
1.0
#269 Feature 269
1.0
#1103 Feature 1103
1.0
#2945 Feature 2945
1.0
#616 Feature 616
1.0
#886 Feature 886
1.0
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1.0
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1.0
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1.0
#47 Feature 47
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
#2405 Feature 2405
0.9
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0.9
#2658 Feature 2658
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
#2848 Feature 2848
0.9
#2410 Feature 2410
0.9
#707 Feature 707
0.9
#265 Feature 265
0.9
#1341 Feature 1341
0.9
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0.9
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0.9
#1195 Feature 1195
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
#48 Feature 48
0.9
#1754 Feature 1754
0.9
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0.9
#875 Feature 875
0.9
#1969 Feature 1969
0.9
#2598 Feature 2598
0.9
#1447 Feature 1447
0.9
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0.9
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0.9
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0.9
#1578 Feature 1578
0.9
#2434 Feature 2434
0.9
#1009 Feature 1009
0.9
#2573 Feature 2573
0.9
#1985 Feature 1985
0.9
#739 Feature 739
0.9
#891 Feature 891
0.9
#1196 Feature 1196
0.9
#447 Feature 447
0.9
#2327 Feature 2327
0.9
#831 Feature 831
0.9
#1246 Feature 1246
0.9
#1275 Feature 1275
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
#344 Feature 344
0.9
#1718 Feature 1718
0.9
#474 Surgical Procedures & Gastrointestinal Issues
0.9
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
#53 Feature 53
0.8
#1185 Feature 1185
0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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Document Content

Bronchiolitis obliterans in workers exposed to flavoring chemicals.
Medical and environmental surveys at microwave popcorn plants and flavoring production plants have revealed a risk for bronchiolitis obliterans in workers exposed to flavoring chemicals. Workers in other food industries may also be at risk. This review summarizes the available information on disease characteristics and natural history and provides information on workplace characteristics associated with disease development. Investigations carried out in flavoring plants in California have identified severely affected current and former workers in four plants. Affected former workers have also been identified at a plant in the Netherlands that manufactured diacetyl, a predominant chemical in butter flavorings which has been implicated as a causal agent for lung disease in microwave popcorn workers. Workers who manufacture or use flavorings can be subjected to repeated intense exposures to flavoring chemicals. Affected workers can progress to severe fixed airways obstruction in as little as 7 months. Since medical treatment is generally ineffective, early identification of affected workers and removal from further exposure, along with control of exposures to protect coworkers, are essential to minimize this hazard.