Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1505

MIN ACTIVATION

0.0

Details List

#1334 Feature 1334

#1314 Feature 1314

#831 Feature 831

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#2689 Feature 2689

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#2665 Feature 2665

#320 Feature 320

#425 Feature 425

#445 Feature 445

#131 Feature 131

#557 Feature 557

#2744 Feature 2744

#2057 Feature 2057

#374 Medical Imaging and Oncology

#773 Feature 773

#325 Feature 325

#1212 Feature 1212

#2266 Feature 2266

#197 Feature 197

#1854 Feature 1854

#2221 Feature 2221

#1591 Feature 1591

#2824 Feature 2824

#2063 Feature 2063

#2735 Feature 2735

#1792 Metastatic Cancer

#1202 Feature 1202

#281 Feature 281

#2666 Feature 2666

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#1423 Feature 1423

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#3031 Feature 3031

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#2171 Molecular and Cellular Biological Processes

#1048 Feature 1048

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#23 Neuronal Circuitry and Cellular Processes

#1732 Feature 1732

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#1105 Feature 1105

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#2914 Feature 2914

#2450 Feature 2450

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#2232 Medical Case Reports & Cancer Research

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#620 Feature 620

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Document Content

Congenital ichthyosiform erythroderma: particulate staining pattern of TGK.
A case of late onset non-bullous congenital ichthyosiform erythroderma (CIE) was studied. This patient was not born as a collodion baby and did not have skin abnormalities until 9-10 years of age. She gradually developed erythroderma and fine scales, callosities of her feet, and a mild ectropion. Since recent work has revealed that in the majority of CIE patients, transglutaminase (TGK) is distributed in the cytoplasm of granular cells and horny cells (11), TGK was studied in our case. It was found that TGK was distributed along the cell periphery of horny cells and also in the cytoplasm of granular cells. In the control skins, TGK was stained along the cell periphery of horny cells and granular cells. The marginal band formation was normal. Involucrine and loricrin, the building materials of the marginal band whose-cross-linking is mediated by TGK, were normally stained in the upper epidermis. Cytoplasmic TGK of granular cells and normal development of the marginal band may serve as a helpful diagnostic marker of CIE, particularly because the often confusing collodion baby of lamellar ichthyosis may lack TGK staining and the marginal band altogether.

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