Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1537

MIN ACTIVATION

0.0

Details List

#1252 Feature 1252

#1061 Feature 1061

#2789 Feature 2789

#2184 Feature 2184

#1219 Feature 1219

#2127 Feature 2127

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#2556 Feature 2556

#2385 Feature 2385

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#2654 Feature 2654

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#366 Feature 366

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#1439 Feature 1439

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#388 Feature 388

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#2875 Feature 2875

#1016 Feature 1016

#2192 Feature 2192

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#316 Feature 316

#1315 Feature 1315

#1571 Feature 1571

#1520 Feature 1520

#156 Feature 156

#530 Feature 530

#2966 Feature 2966

#1910 Feature 1910

#813 Feature 813

#2552 Feature 2552

#1541 Feature 1541

#3064 Surgical Complications and Physiological Stress

#1633 Feature 1633

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#619 Feature 619

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#2068 Feature 2068

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#1083 Feature 1083

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#2272 Feature 2272

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#2975 Feature 2975

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#205 Feature 205

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#1189 Feature 1189

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#240 Feature 240

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#1803 Feature 1803

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#2104 Feature 2104

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#591 Feature 591

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#888 Feature 888

#1405 Feature 1405

#838 Feature 838

#1267 Feature 1267

#2203 Feature 2203

#2502 Feature 2502

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#922 Feature 922

#2213 Feature 2213

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#2629 Feature 2629

#2399 Feature 2399

#1710 Feature 1710

#2313 Feature 2313

#563 Feature 563

#1639 Feature 1639

#1228 Feature 1228

#2371 Feature 2371

#1901 Feature 1901

#2960 Feature 2960

#2550 Feature 2550

#2527 Feature 2527

#825 Feature 825

#2176 Feature 2176

#2011 Feature 2011

#1351 Feature 1351

#542 Feature 542

#1812 Feature 1812

#383 Feature 383

#1194 Feature 1194

#1822 Feature 1822

#2423 Feature 2423

#1745 Feature 1745

#2372 Feature 2372

#245 Feature 245

#1284 Feature 1284

#759 Feature 759

#3025 Feature 3025

#972 Feature 972

#2054 Feature 2054

#1305 Feature 1305

#2110 Feature 2110

#866 Feature 866

#274 Feature 274

#840 Feature 840

#2444 Feature 2444

#2253 Feature 2253

#3001 Feature 3001

#414 Feature 414

#467 Feature 467

#2306 Feature 2306

#2440 Feature 2440

#1056 Feature 1056

#2521 Feature 2521

#1280 Feature 1280

#926 Feature 926

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#2980 Feature 2980

#2772 Feature 2772

#2327 Feature 2327

#2710 Feature 2710

#768 Feature 768

#1502 Feature 1502

#1602 Feature 1602

#1220 Feature 1220

#2894 Feature 2894

#2298 Feature 2298

#925 Feature 925

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#2179 Feature 2179

#3012 Feature 3012

#2332 Feature 2332

#1201 Feature 1201

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#2217 Feature 2217

#2973 Feature 2973

#420 Feature 420

#2598 Feature 2598

#470 Feature 470

#2992 Feature 2992

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#246 Feature 246

#130 Feature 130

#377 Feature 377

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#994 Feature 994

#2722 Feature 2722

#160 Feature 160

#1047 Feature 1047

#1572 Feature 1572

#2271 Feature 2271

#1605 Feature 1605

#1074 Feature 1074

#2902 Feature 2902

#147 Feature 147

#1737 Feature 1737

#258 Feature 258

#400 Feature 400

#995 Feature 995

#2412 Feature 2412

#1470 Feature 1470

#2031 Feature 2031

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#1454 Feature 1454

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#1030 Feature 1030

#2121 Feature 2121

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#186 Feature 186

#2736 Feature 2736

#217 Feature 217

#753 Feature 753

#2819 Feature 2819

#2455 Feature 2455

#2037 Feature 2037

#601 Feature 601

#235 Feature 235

#1288 Feature 1288

#669 Feature 669

#1027 Feature 1027

#2883 Feature 2883

#586 Feature 586

#2200 Feature 2200

#1172 Feature 1172

#1389 Feature 1389

#612 Feature 612

#1937 Feature 1937

#1048 Feature 1048

#1032 Feature 1032

#2443 Feature 2443

#2387 Feature 2387

#1829 Feature 1829

#1387 Feature 1387

#1678 Feature 1678

#1053 Feature 1053

#161 Feature 161

#764 Feature 764

#895 Feature 895

#540 Feature 540

#980 Feature 980

#1655 Feature 1655

#956 Feature 956

#494 Feature 494

#595 Feature 595

#2837 Feature 2837

#1313 Feature 1313

#1148 Feature 1148

#1623 Feature 1623

#489 Feature 489

#1213 Feature 1213

#998 Feature 998

#2546 Feature 2546

#124 Feature 124

#270 Feature 270

#512 Feature 512

#2694 Feature 2694

#2648 Feature 2648

#2103 Feature 2103

#118 Feature 118

#1687 Feature 1687

#1879 Feature 1879

#645 Feature 645

#1923 Feature 1923

#2312 Feature 2312

#744 Feature 744

#1721 Feature 1721

#1543 Feature 1543

#1132 Feature 1132

#3068 Feature 3068

#1587 Feature 1587

#1615 Feature 1615

#2485 Feature 2485

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#423 Feature 423

#916 Feature 916

#1621 Feature 1621

#206 Feature 206

#2136 Feature 2136

#3044 Feature 3044

#1667 Feature 1667

#1675 Feature 1675

#671 Feature 671

#571 Feature 571

#660 Feature 660

#2040 Feature 2040

#2936 Feature 2936

#1887 Feature 1887

#2309 Feature 2309

#2581 Feature 2581

#945 Feature 945

#2256 Feature 2256

#1750 Feature 1750

#1850 Feature 1850

#1044 Feature 1044

#1432 Feature 1432

#2286 Feature 2286

#1834 Feature 1834

#837 Feature 837

#1320 Feature 1320

#673 Feature 673

#2406 Feature 2406

#2979 Feature 2979

#2570 Feature 2570

#3000 Feature 3000

#976 Feature 976

#2034 Feature 2034

#2491 Feature 2491

#3053 Feature 3053

#1080 Feature 1080

#1429 Feature 1429

#735 Feature 735

#2617 Feature 2617

#2148 Feature 2148

#2814 Feature 2814

#1514 Feature 1514

#2145 Feature 2145

#1086 Feature 1086

#2397 Feature 2397

#422 Feature 422

#3042 Feature 3042

#2503 Feature 2503

#2023 Feature 2023

#320 Feature 320

#1294 Feature 1294

#875 Feature 875

#3026 Feature 3026

#1790 Feature 1790

#2892 Feature 2892

#987 Feature 987

#412 Feature 412

#2461 Feature 2461

#1038 Feature 1038

#1626 Feature 1626

#1773 Feature 1773

#2018 Feature 2018

#2870 Feature 2870

#1347 Feature 1347

#480 Feature 480

#2178 Feature 2178

#1260 Feature 1260

#2239 Feature 2239

#1999 Feature 1999

#1065 Feature 1065

#3057 Feature 3057

#1025 Feature 1025

#2826 Feature 2826

#2915 Feature 2915

#401 Feature 401

#1713 Feature 1713

#2730 Feature 2730

#1046 Feature 1046

#1809 Feature 1809

#1692 Feature 1692

#2554 Feature 2554

#415 Feature 415

#712 Feature 712

#1427 Feature 1427

#2227 Feature 2227

#1559 Feature 1559

#1752 Feature 1752

#2365 Feature 2365

#2780 Feature 2780

#2541 Feature 2541

#289 Feature 289

#2030 Feature 2030

#841 Feature 841

#1534 Feature 1534

#1524 Feature 1524

#222 Feature 222

#2446 Feature 2446

#2478 Feature 2478

#2036 Feature 2036

#394 Feature 394

#1301 Feature 1301

#2258 Feature 2258

#2099 Feature 2099

#1015 Feature 1015

#2925 Feature 2925

#970 Feature 970

#1774 Feature 1774

#2862 Feature 2862

#848 Feature 848

#2838 Feature 2838

#1781 Feature 1781

#1996 Feature 1996

#784 Feature 784

#1956 Feature 1956

#1624 Feature 1624

#2221 Feature 2221

#1001 Feature 1001

#2338 Feature 2338

#1501 Feature 1501

#481 Feature 481

#1197 Feature 1197

#178 Feature 178

#1395 Feature 1395

#1359 Feature 1359

#2038 Feature 2038

#2083 Feature 2083

#2329 Feature 2329

#1235 Feature 1235

#702 Feature 702

#1563 Feature 1563

#522 Feature 522

#317 Feature 317

#1990 Feature 1990

#1302 Sensing and Detection Technologies

#2794 Feature 2794

#1666 Feature 1666

#1013 Feature 1013

#100 Feature 100

#373 Feature 373

#1054 Feature 1054

#1760 Feature 1760

#663 Feature 663

#2777 Feature 2777

#294 Feature 294

#2660 Feature 2660

#3019 Feature 3019

#3054 Feature 3054

#889 Feature 889

#983 Feature 983

#2411 Feature 2411

#2726 Feature 2726

#259 Feature 259

#2015 Feature 2015

#2000 Feature 2000

#1535 Feature 1535

#292 Feature 292

#342 Feature 342

#947 Feature 947

#649 Feature 649

#921 Feature 921

#1006 Feature 1006

#1403 Feature 1403

#2191 Feature 2191

#2391 Feature 2391

#2274 Feature 2274

#2137 Feature 2137

#1283 Feature 1283

#1186 Feature 1186

#2584 Feature 2584

#1669 Feature 1669

#900 Feature 900

#1836 Feature 1836

#760 Feature 760

#2624 Feature 2624

#1959 Feature 1959

#2941 Feature 2941

#1637 Feature 1637

#1873 Feature 1873

#933 Feature 933

#1600 Feature 1600

#1815 Feature 1815

#859 Feature 859

#2259 Feature 2259

#2364 Feature 2364

#1734 Feature 1734

#2090 Feature 2090

#1135 Feature 1135

#2512 Feature 2512

#628 Feature 628

#2974 Feature 2974

#1489 Feature 1489

#2917 Feature 2917

#2317 Feature 2317

#1455 Feature 1455

#1037 Feature 1037

#2520 Feature 2520

#1011 Feature 1011

#2146 Feature 2146

#1078 Feature 1078

#2522 Feature 2522

#2535 Feature 2535

#624 Feature 624

#298 Feature 298

#1504 Feature 1504

#2538 Feature 2538

#446 Feature 446

#166 Feature 166

#2879 Feature 2879

#2047 Feature 2047

#918 Feature 918

#2012 Feature 2012

#2303 Feature 2303

#1510 Feature 1510

#1719 Feature 1719

#687 Feature 687

#621 Feature 621

#1681 Feature 1681

#484 Feature 484

#239 Feature 239

#990 Feature 990

#1823 Feature 1823

#2177 Feature 2177

#3034 Feature 3034

#682 Feature 682

#2872 Feature 2872

#148 Feature 148

#973 Feature 973

#1088 Feature 1088

#772 Feature 772

#1787 Feature 1787

#891 Feature 891

#2748 Feature 2748

#1588 Feature 1588

#354 Feature 354

#1966 Feature 1966

#1394 Feature 1394

#639 Feature 639

#207 Feature 207

#1738 Feature 1738

#722 Feature 722

#1868 Feature 1868

#2631 Feature 2631

#504 Feature 504

#3008 Feature 3008

#2445 Feature 2445

#279 Feature 279

#2044 Feature 2044

#2847 Feature 2847

#600 Feature 600

#906 Feature 906

#2457 Feature 2457

#2779 Feature 2779

#1222 Feature 1222

#1075 Feature 1075

#2744 Feature 2744

#2669 Feature 2669

#1463 Feature 1463

#284 Feature 284

#2728 Feature 2728

#1275 Feature 1275

#1045 Feature 1045

#1650 Feature 1650

#1043 Feature 1043

#1376 Feature 1376

#110 Feature 110

#1557 Feature 1557

#2518 Feature 2518

#610 Feature 610

#1646 Feature 1646

#1950 Feature 1950

#2689 Feature 2689

#158 Feature 158

#1644 Feature 1644

#1451 Feature 1451

#501 Feature 501

#2095 Feature 2095

#1974 Feature 1974

#113 Feature 113

#1870 Feature 1870

#1370 Feature 1370

#2898 Feature 2898

#1255 Feature 1255

#1490 Feature 1490

#2149 Feature 2149

#3059 Feature 3059

#2314 Feature 2314

#1661 Feature 1661

#2859 Feature 2859

#1421 Feature 1421

#538 Feature 538

#2750 Feature 2750

#546 Feature 546

#417 Feature 417

#2867 Feature 2867

#2164 Feature 2164

#936 Feature 936

#1900 Feature 1900

#127 Feature 127

#2566 Feature 2566

#527 Feature 527

#2139 Feature 2139

#930 Feature 930

#2135 Feature 2135

#2834 Feature 2834

#455 Feature 455

#1631 Feature 1631

#1199 Feature 1199

#2003 Feature 2003

#3020 Feature 3020

#644 Feature 644

#2212 Feature 2212

#715 Feature 715

#1153 Feature 1153

#1070 Feature 1070

#364 Feature 364

#260 Feature 260

#2102 Feature 2102

#1059 Feature 1059

#339 Feature 339

#647 Feature 647

#809 Feature 809

#818 Feature 818

#309 Feature 309

#1513 Feature 1513

#1929 Feature 1929

#2702 Feature 2702

#101 Feature 101

#2087 Feature 2087

#989 Feature 989

#444 Feature 444

#1533 Feature 1533

#833 Feature 833

#2530 Feature 2530

#1855 Feature 1855

#2367 Feature 2367

#204 Feature 204

#864 Feature 864

#573 Feature 573

#737 Feature 737

#2919 Feature 2919

#2369 Feature 2369

#2350 Feature 2350

#338 Feature 338

#856 Feature 856

#1180 Feature 1180

#216 Feature 216

#308 Feature 308

#2509 Feature 2509

#656 Feature 656

#106 Feature 106

#1799 Feature 1799

#2547 Feature 2547

#965 Feature 965

#3002 Feature 3002

#1599 Feature 1599

#742 Feature 742

#1249 Feature 1249

#2549 Feature 2549

#1925 Feature 1925

#2825 Feature 2825

#2459 Feature 2459

#2305 Feature 2305

#2360 Feature 2360

#1468 Feature 1468

#1816 Feature 1816

#2222 Feature 2222

#2821 Feature 2821

#2947 Feature 2947

#674 Feature 674

#1807 Feature 1807

#349 Feature 349

#508 Feature 508

#428 Feature 428

#1411 Feature 1411

#223 Feature 223

#2463 Feature 2463

#1337 Feature 1337

#2307 Feature 2307

#913 Feature 913

#724 Feature 724

#1307 Feature 1307

#2160 Feature 2160

#684 Feature 684

#472 Feature 472

#834 Feature 834

#2402 Feature 2402

#969 Feature 969

#1845 Feature 1845

#1548 Feature 1548

#1562 Feature 1562

#1221 Feature 1221

#1755 Feature 1755

#599 Feature 599

#2376 Feature 2376

#2977 Feature 2977

#2643 Feature 2643

#2320 Feature 2320

#1894 Feature 1894

#392 Feature 392

#2019 Feature 2019

#2005 Feature 2005

#2304 Feature 2304

#1796 Feature 1796

#1323 Feature 1323

#2940 Feature 2940

#447 Feature 447

#2228 Feature 2228

#1437 Feature 1437

#1466 Feature 1466

#2740 Feature 2740

#853 Feature 853

#2144 Feature 2144

#2983 Feature 2983

#266 Feature 266

#1947 Feature 1947

#2249 Feature 2249

#119 Feature 119

#1749 Feature 1749

#1914 Feature 1914

#2393 Feature 2393

#2544 Feature 2544

#1732 Feature 1732

#137 Feature 137

#2236 Feature 2236

#2651 Feature 2651

#1784 Feature 1784

#2775 Feature 2775

#2424 Feature 2424

#1613 Feature 1613

#398 Feature 398

#1814 Feature 1814

#1764 Feature 1764

#1909 Feature 1909

#589 Feature 589

#2108 Feature 2108

#1345 Feature 1345

#2845 Feature 2845

#2786 Feature 2786

#1668 Feature 1668

#2820 Feature 2820

#1889 Feature 1889

#1102 Feature 1102

#1573 Feature 1573

#1779 Feature 1779

#325 Feature 325

#1989 Feature 1989

#2808 Feature 2808

#689 Feature 689

#2211 Feature 2211

#1108 Feature 1108

#3069 Feature 3069

#2205 Feature 2205

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#608 Feature 608

#2382 Feature 2382

#747 Feature 747

#1552 Feature 1552

#511 Feature 511

#2117 Feature 2117

#1497 Feature 1497

#1777 Feature 1777

#2296 Feature 2296

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#262 Feature 262

#227 Feature 227

#1540 Feature 1540

#2573 Feature 2573

#2632 Feature 2632

#2480 Feature 2480

#492 Feature 492

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#692 Feature 692

#2210 Feature 2210

#1413 Feature 1413

#2909 Feature 2909

#190 Feature 190

#630 Feature 630

#2958 Feature 2958

#1730 Feature 1730

#2787 Feature 2787

#184 Feature 184

#1805 Feature 1805

#761 Feature 761

#1343 Feature 1343

#2529 Feature 2529

#219 Feature 219

#1120 Feature 1120

#2251 Feature 2251

#655 Feature 655

#932 Feature 932

#2738 Feature 2738

#1117 Feature 1117

#2782 Feature 2782

#1297 Feature 1297

#120 Feature 120

#1131 Feature 1131

#2295 Feature 2295

#208 Feature 208

#170 Feature 170

#1690 Feature 1690

#257 Feature 257

#198 Feature 198

#1287 Feature 1287

#2601 Feature 2601

#1944 Feature 1944

#1592 Feature 1592

#1899 Feature 1899

#2681 Feature 2681

#543 Feature 543

#1933 Feature 1933

#1002 Feature 1002

#2564 Feature 2564

#2760 Feature 2760

#403 Feature 403

#1584 Feature 1584

#1373 Feature 1373

#1480 Feature 1480

#653 Feature 653

#1622 Feature 1622

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#2589 Feature 2589

#2244 Feature 2244

#1346 Feature 1346

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#3030 Feature 3030

#730 Feature 730

#1206 Feature 1206

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#1300 Feature 1300

#1895 Feature 1895

#770 Feature 770

#2190 Feature 2190

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#1003 Feature 1003

#2022 Feature 2022

#368 Feature 368

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#977 Feature 977

#2650 Feature 2650

#2380 Feature 2380

#871 Feature 871

#199 Feature 199

#183 Feature 183

#177 Feature 177

#966 Feature 966

#1942 Feature 1942

#2331 Feature 2331

#852 Feature 852

#408 Feature 408

#2415 Feature 2415

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#910 Feature 910

#1635 Feature 1635

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#1123 Feature 1123

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#358 Feature 358

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#1840 Feature 1840

#2752 Feature 2752

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#1007 Feature 1007

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#2968 Feature 2968

#863 Feature 863

#141 Feature 141

#1997 Feature 1997

#2519 Feature 2519

#3027 Feature 3027

#1818 Feature 1818

#176 Feature 176

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#2284 Feature 2284

#2114 Feature 2114

#139 Feature 139

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#203 Feature 203

#109 Feature 109

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#584 Feature 584

#2869 Feature 2869

#726 Feature 726

#1236 Feature 1236

#2641 Feature 2641

#332 Feature 332

#427 Feature 427

#2691 Feature 2691

#1806 Feature 1806

#311 Feature 311

#1430 Feature 1430

#556 Feature 556

#2324 Feature 2324

#2630 Feature 2630

#2813 Feature 2813

#552 Feature 552

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#2713 Feature 2713

#1842 Feature 1842

#1782 Feature 1782

#2623 Feature 2623

#2976 Feature 2976

#801 Feature 801

#201 Feature 201

#1575 Feature 1575

#1907 Feature 1907

#2343 Feature 2343

#283 Feature 283

#1864 Feature 1864

#1145 Feature 1145

#244 Feature 244

#907 Feature 907

#1983 Feature 1983

#1616 Feature 1616

#465 Feature 465

#2724 Feature 2724

#1237 Feature 1237

#757 Feature 757

#1386 Feature 1386

#1443 Feature 1443

#846 Feature 846

#2506 Feature 2506

#1176 Feature 1176

#817 Feature 817

#2374 Feature 2374

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#1720 Feature 1720

#607 Feature 607

#3024 Feature 3024

#2297 Feature 2297

#104 Feature 104

#2220 Feature 2220

#2414 Feature 2414

#2649 Feature 2649

#1595 Feature 1595

#2186 Feature 2186

#1322 Feature 1322

#2610 Feature 2610

#2594 Feature 2594

#2020 Feature 2020

#195 Feature 195

#2232 Medical Case Reports & Cancer Research

#330 Feature 330

#1932 Feature 1932

#1274 Feature 1274

#2472 Feature 2472

#1217 Feature 1217

#1049 Feature 1049

#1166 Feature 1166

#1594 Feature 1594

#1519 Feature 1519

#2628 Feature 2628

#1663 Feature 1663

#1371 Feature 1371

#2557 Feature 2557

#1792 Metastatic Cancer

#1212 Feature 1212

#611 Feature 611

#1871 Feature 1871

#1239 Feature 1239

#2132 Feature 2132

#132 Feature 132

#247 Feature 247

#2741 Feature 2741

#960 Feature 960

#102 Feature 102

#901 Feature 901

#1040 Feature 1040

#967 Feature 967

#2240 Feature 2240

#1503 Feature 1503

#2141 Feature 2141

#2214 Feature 2214

#1391 Feature 1391

#2639 Feature 2639

#2667 Feature 2667

#1825 Feature 1825

#1938 Feature 1938

#827 Feature 827

#2513 Feature 2513

#362 Feature 362

#514 Feature 514

#267 Feature 267

#1531 Feature 1531

#2017 Feature 2017

#187 Feature 187

#1309 Feature 1309

#1318 Feature 1318

#2793 Feature 2793

#2398 Feature 2398

#1652 Feature 1652

#174 Feature 174

#865 Feature 865

#633 Feature 633

#153 Feature 153

#2026 Feature 2026

#2218 Feature 2218

#854 Feature 854

#1210 Feature 1210

#3033 Feature 3033

#1948 Feature 1948

#290 Feature 290

#2678 Feature 2678

#23 Neuronal Circuitry and Cellular Processes

#2180 Feature 2180

#594 Feature 594

#569 Feature 569

#923 Feature 923

#2477 Feature 2477

#2170 Feature 2170

#1995 Feature 1995

#1987 Feature 1987

#2293 Feature 2293

#1265 Feature 1265

#1161 Feature 1161

#1071 Feature 1071

#620 Feature 620

#988 Feature 988

#2163 Feature 2163

#2162 Feature 2162

#855 Feature 855

#2064 Feature 2064

#1709 Feature 1709

#904 Feature 904

#2311 Feature 2311

#234 Feature 234

#974 Feature 974

#2464 Feature 2464

#1835 Feature 1835

#1975 Feature 1975

#598 Feature 598

#2368 Feature 2368

#2604 Feature 2604

#2585 Feature 2585

#271 Feature 271

#372 Feature 372

#2767 Feature 2767

#2315 Feature 2315

#2768 Feature 2768

#2091 Feature 2091

#2908 Feature 2908

#2435 Feature 2435

#1408 Feature 1408

#2873 Feature 2873

#471 Feature 471

#2761 Feature 2761

#2493 Feature 2493

#1245 Feature 1245

#1618 Feature 1618

#2375 Feature 2375

#2085 Feature 2085

#123 Feature 123

#790 Feature 790

#1340 Feature 1340

#1191 Feature 1191

#2511 Feature 2511

#606 Feature 606

#719 Feature 719

#2447 Feature 2447

#2235 Feature 2235

#2751 Feature 2751

#632 Feature 632

#964 Feature 964

#1354 Feature 1354

#3015 Feature 3015

#2289 Feature 2289

#2458 Feature 2458

#200 Feature 200

#2226 Feature 2226

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Document Content

Microvascular and endothelial function for risk prediction in dengue: an observational study.
Dengue infection can result in a wide spectrum of disease. The defining feature of severe disease is increased capillary permeability, which can lead to hypovolaemic shock. Microvascular and endothelial dysfunction might underlie hypovolaemic shock, but they have not been assessed clinically. We aimed to investigate the use of microvascular assessment as a prognostic method in dengue. This is an ongoing prospective observational study that aims to recruit 300 participants: children over the age of 3 years and adults presenting to two outpatient departments in Vietnam with fever of less than 72 h duration and suspected dengue, and patients admitted to hospital with warning signs or severe disease. Participants are being clinically assessed daily for 6 days, and 2 weeks later. Microvascular imaging using sublingual sidestream darkfield imaging (SDF) and endothelial function testing using peripheral artery tonometry are being performed at enrolment, defervescence, and follow-up To date, 167 patients have been recruited (92 outpatient arm, 75 inpatient arm, median age 27 years [IQR 21-33], 78 male [47%]). Dengue has been confirmed in 67 individuals in the outpatient arm, of whom 29 (43%) developed warning signs, three (4%) developed severe disease, and 35 had uncomplicated dengue; the other 25 outpatients (27%) were diagnosed as other febrile illness. At enrolment, the reactive hyperaemic index, a marker of endothelial function, was lowest in the patients who went on to develop severe dengue (median 1·54, IQR 1·36-1·77) followed by those who developed warning signs (1·78, 1·43-2·36) and then uncomplicated dengue (2·18, 1·65-2·24). Initial SDF results showed a lower proportion of perfused vessels and mean flow index during the febrile phase of dengue compared with follow-up, and were worst in the severe group at defervescence. This study of vascular function at serial timepoints in dengue is, to our knowledge, the first and most comprehensive. Our preliminary results suggest that microvascular and endothelial dysfunction are associated with severity of dengue, and occur before the appearance of severe clinical manifestations. These techniques might be useful in risk prediction in dengue. A limitation is that a formal sample size could not be calculated because no previous microvascular data in dengue exist. Wellcome Trust.

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