PRISMΔDB

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Active Features

1505

0.0
Details List
#1608 Feature 1608
2.9
#2217 Feature 2217
2.9
#1405 Feature 1405
2.7
#1566 Feature 1566
2.7
#619 Feature 619
2.6
#1336 Feature 1336
2.6
#247 Feature 247
2.4
#392 Feature 392
2.4
#2398 Feature 2398
2.4
#1185 Feature 1185
2.2
#2135 Feature 2135
2.2
#2383 Feature 2383
2.2
#120 Feature 120
2.1
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2.1
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2.1
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2.1
#2088 Feature 2088
2.0
#2454 Feature 2454
1.9
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1.9
#2303 Feature 2303
1.9
#2285 Feature 2285
1.8
#440 Feature 440
1.8
#2855 Feature 2855
1.8
#2999 Feature 2999
1.8
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1.7
#2096 Feature 2096
1.6
#2596 Feature 2596
1.6
#2403 Feature 2403
1.6
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1.6
#2266 Feature 2266
1.6
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1.5
#585 Feature 585
1.5
#76 Feature 76
1.5
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1.5
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1.5
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1.5
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1.5
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1.5
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
#1102 Feature 1102
1.4
#2018 Feature 2018
1.4
#775 Feature 775
1.4
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1.3
#2423 Feature 2423
1.3
#2218 Feature 2218
1.3
#2408 Feature 2408
1.3
#2973 Feature 2973
1.3
#1285 Feature 1285
1.3
#477 Feature 477
1.3
#3051 Feature 3051
1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
#2787 Feature 2787
1.3
#2441 Feature 2441
1.3
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1.3
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1.3
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1.3
#2768 Feature 2768
1.3
#493 Feature 493
1.2
#2916 Feature 2916
1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
#1540 Feature #1540
1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
#2632 Feature 2632
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
#2640 Feature 2640
0.9
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0.9
#1545 Feature 1545
0.9
#2730 Feature 2730
0.9
#2161 Medical/Scientific Discourse with Ethical/Social Implications
0.9
#54 Feature 54
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
#1054 Feature 1054
0.9
#2369 Feature 2369
0.9
#2661 Feature 2661
0.9
#96 Feature 96
0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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0.7
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Document Content

Mild subclinical hypothyroidism is associated with paediatric dyslipidaemia.
There is a lack of consensus on the cardiometabolic consequences of mild subclinical hypothyroidism (SCH) among children. The objective of the current study was to compare lipid profiles in children with mild SCH with those of euthyroid children. Retrospective medical record review. Children (ages 2-18 years) who had undergone simultaneous measurement of TSH, free thyroxine (T4) and lipids. Lipids in children with mild SCH (TSH 5-<10 mIU/L and normal free T4, n = 228) were compared with those in euthyroid children (n = 1215). TSH level was positively associated with total cholesterol and nonhigh density lipoprotein (non-HDL) cholesterol [β 0.05(0.03-0.08), P < .0001 and β 0.05(0.03-0.08), P < .0001, respectively]. Total cholesterol was significantly higher in children and adolescents with mild SCH compared with euthyroid children (4.43 ± 1.14 mmol/L vs 4.2 ± 0.85 mmol/L, P = .0005). Similarly, non-HDL cholesterol level was also higher in children with mild SCH relative to euthyroid children (3.08 ± 1.14 mmol/L vs 2.91 ± 0.8 mmol/L, P = .001). The adjusted odds ratio of having elevated total cholesterol and elevated non-HDL cholesterol was greater in children with mild SCH compared with euthyroid children (OR 1.88, 95% CI; 1.28-2.73; P = .001 and 1.72, 95% CI 1.2-2.5; P = .003, respectively). The presence of thyroid autoimmunity was not associated with higher rates of dyslipidaemia. Mild SCH in children and adolescents was associated with higher rates of elevated total cholesterol and elevated non-HDL cholesterol. Randomized placebo controlled studies are warranted to determine if treatment of mild SCH in children leads to improvement in lipid profile.