PRISMΔDB

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Active Features

1521

0.0
Details List
#2393 Feature 2393
2.5
#92 Feature 92
2.2
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2.2
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2.2
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2.1
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2.1
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2.1
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2.0
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2.0
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2.0
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2.0
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2.0
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2.0
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2.0
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1.9
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1.9
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1.9
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1.9
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1.8
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1.8
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1.8
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1.7
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1.7
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1.7
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1.7
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1.6
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1.6
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1.6
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1.6
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1.6
#3064 Surgical Complications and Physiological Stress
1.6
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1.6
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1.6
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1.6
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1.6
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1.5
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1.5
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1.5
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1.5
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.4
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.3
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.2
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.1
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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1.0
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.9
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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0.8
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Document Content

Atrial natriuretic peptide in brain preoptic areas: implications for fluid and salt homeostasis.
The influence of adrenalectomy and mineralocorticoid and glucocorticoid treatment on atrial natriuretic peptide (ANP) concentration of 18 microdissected rat brain nuclei was investigated. Adrenalectomy increased ANP levels highly in those brain areas that control water intake (the subfornical organ and supraoptic nucleus) and in the drinking center (the perifornical nucleus and the lateral hypothalamus). In all of these brain regions, aldosterone elevated ANP levels in intact animals. Adrenalectomy decreased ANP levels markedly in the OVLT and preoptic periventricular nucleus, which constitute the so-called AV3V region. The ANP level of these two brain areas was nearly restored to baseline levels both after administration of sodium chloride and after replacement of aldosterone, whereas dexamethasone treatment failed to have any effect.