Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1474

MIN ACTIVATION

0.0

Details List

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#3064 Surgical Complications and Physiological Stress

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#420 Feature 420

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#174 Feature 174

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#2183 Feature 2183

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#201 Feature 201

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#1457 Feature 1457

#1477 Feature 1477

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#2121 Feature 2121

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#1142 Feature 1142

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#1525 Feature 1525

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#1692 Feature 1692

#403 Feature 403

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#2746 Feature 2746

#537 Feature 537

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#2802 Feature 2802

#1234 Feature 1234

#773 Feature 773

#582 Feature 582

#225 Feature 225

#971 Feature 971

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#1851 Feature 1851

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#120 Feature 120

#3002 Feature 3002

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#2275 Feature 2275

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#126 Feature 126

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#671 Feature 671

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#2061 Feature 2061

#2771 Feature 2771

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#1123 Feature 1123

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#1543 Feature 1543

#1815 Feature 1815

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#840 Feature 840

#2077 Feature 2077

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#935 Feature 935

#1442 Feature 1442

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#1658 Feature 1658

#1159 Feature 1159

#1194 Feature 1194

#1847 Feature 1847

#2913 Feature 2913

#1245 Feature 1245

#3022 Feature 3022

#1053 Feature 1053

#1335 Feature 1335

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#2222 Feature 2222

#2039 Feature 2039

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#2852 Feature 2852

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#2811 Feature 2811

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#2221 Feature 2221

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#1712 Feature 1712

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#1619 Feature 1619

#2797 Feature 2797

#3020 Feature 3020

#2177 Feature 2177

#800 Feature 800

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#2007 Developmental Disparities & Intervention

#1600 Feature 1600

#1553 Feature 1553

#407 Feature 407

#2712 Feature 2712

#1703 Feature 1703

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#1043 Feature 1043

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#1323 Feature 1323

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#208 Feature 208

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#2428 Feature 2428

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#2220 Feature 2220

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#2776 Feature 2776

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#2530 Feature 2530

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#3049 Feature 3049

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#2101 Feature 2101

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#622 Feature 622

#2555 Feature 2555

#775 Feature 775

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#2951 Feature 2951

#1301 Feature 1301

#629 Feature 629

#1040 Feature 1040

#2232 Medical Case Reports & Cancer Research

#870 Feature 870

#882 Feature 882

#444 Feature 444

#2814 Feature 2814

#2229 Feature 2229

#1345 Feature 1345

#128 Feature 128

#2465 Feature 2465

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#121 Feature 121

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#3035 Feature 3035

#2503 Feature 2503

#1710 Feature 1710

#2623 Feature 2623

#2425 Feature 2425

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#784 Feature 784

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#2242 Feature 2242

#2343 Feature 2343

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#1577 Feature 1577

#2633 Feature 2633

#1718 Feature 1718

#1176 Feature 1176

#1346 Feature 1346

#2999 Feature 2999

#584 Feature 584

#1734 Feature 1734

#877 Feature 877

#606 Feature 606

#147 Feature 147

#1905 Feature 1905

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Document Content

The value of bronchoalveolar lavage for discrimination between healthy and diseased individuals.
Bronchoalveolar lavage (BAL) is standard diagnostic procedure. Procedural recommendations have been made by pneumological societies including normal values for interpretation of BAL cytology. These normal values derive from small studies in healthy volunteers and have never been analysed for their sensitivity and specificity. This study aims to analyse sensitivity and specificity of these normal values by assessing lavage cell composition in healthy and diseased individuals. More than 6000 BAL were retrospectively analysed for their cellular distribution including BALs of 250 healthy individuals. All BALs were obtained under similar conditions. Bronchoalveolar lavage cytology of healthy individuals mirrors data from previous studies with smoking being the most important manipulator of BAL cytology. Analyses of proposed normal values demonstrate specificity between 80% and 95%, whereas sensitivity ranges between 35% and 65%. Using different mathematical models, a value summing up the differences to ATS-proposed normal values of the cytological pattern was found to best discriminate between healthy and diseased individuals with a sensitivity of nearly 60% with a predefined specificity of 95%. In summary, our analysis confirmed prior results for healthy volunteers and enlarged these findings by analysing sensitivity and specificity of lavage results in an independent validation cohort of diseased individuals. Thereby, the study may influence the acceptance of BAL in the diagnostic workup of individuals with pulmonary diseases. Additionally, the study proposes a novel value that facilitates lavage interpretation and may therefore be useful in further studies.

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