PRISMΔDB
SAE MODEL #2

FEATURE 1792

/ Metastatic Cancer
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This page shows the detailed analysis of a specific feature in the Sparse Autoencoder (SAE). It includes the semantic interpretation generated by the LLM, the top activating documents that trigger this feature, and statistical metrics like density and activation distribution.

Semantic Interpretation
gemma3:12b #11

The neuron strongly activates in contexts describing cancer that has spread from its original site to other parts of the body, particularly to bone, liver, muscle, and the meninges. The examples consistently involve descriptions of diagnostic procedures (CT scans, biopsies, scintigraphy), treatment options (liver transplantation, esophagectomy), and the progression of the disease. The specific types of cancer mentioned (melanoma, prostate, breast, colorectal, pancreatic, gastric) are less important than the overarching theme of cancer metastasis. The presence of terms like 'metastasis,' 'bone metastases,' 'liver metastases,' 'skeletal muscle metastasis,' and 'leptomeningeal metastasis' are key indicators. The descriptions often include details about diagnostic imaging, surgical interventions, and the monitoring of tumor markers. The negative examples focus on unrelated medical topics like cardiac surgery, lipid management, and molecular biology, which lack this metastatic cancer theme.

STATISTICS & DISTRIBUTION
Statistics Explained

Density
Fraction of documents where this feature activates at least once.
Higher density = feature appears frequently across the dataset.

Peak Activation
Maximum activation value observed for this feature over all documents.

Activation Histogram
Distribution of all activation values for this feature. Each bar represents a bin (range) of values, and its height shows how many documents fall in that range.

Density
0.02900
Peak Act
3.71
0.0 Max
Global Context
TOP ACTIVATING CONTEXTS
DOC #594 ANALYZE
ACT: 3.7090
Bone Metabolism of the Patient with a Malignant Melanoma during the Entry Examination and the Check-up of Whole-body Bone Scintigraphy. Malignant melanoma is a malignancy located predominantly in the skin and the incidence of melanoma increases. We compared the markers of bone metabolism - osteocalcin (OC), beta-carboxyterminal cross-linked telope…
DOC #94 ANALYZE
ACT: 3.2574
CT of intracranial metastases with skull and scalp involvement. Twenty-eight persons with contiguous intracranial skull, and often extracranial metastatic disease are reported. These lesions comprised 7.6% of a series of 250 consecutive patients with intracranial metastatic disease. Only three of 28 patients had other intracranial lesions and only…
DOC #44 ANALYZE
ACT: 2.8195
[Clinical analysis of liver transplantation in treatment of liver metastatic cancer]. To evaluate the feasibility and outcome of liver transplantation in the treatment of liver metastatic cancer. Four patients with pathologically confirmed liver metastatic cancer underwent liver transplantation, including one of liver metastases from pancreatic en…
DOC #889 ANALYZE
ACT: 2.6015
[A case of skeletal muscle metastasis on the left thigh after esophagectomy for esophageal adenocarcinoma in Barrett' s esophagus]. We report the case of a 45-year-old man with advanced esophageal adenocarcinoma in Barrett's esophagus. After neoadjuvant chemotherapy using S-1, docetaxel, and cisplatin, the patient underwent thoracoscopic esophagec…
DOC #71 ANALYZE
ACT: 2.3519
Leptomeningeal metastasis with urological presentation. The incidence of clinical leptomeningeal metastases from non-neurologic solid tumour is generally increasing as a result of better survival of systemic cancer with chemotherapy. Their presentation varies according to the neurological involvement. A case of leptomeningeal metastasis from an un…
DOC #543 ANALYZE
ACT: 2.3491
Lymph node biopsy does not impair survival after therapeutic dissection for palpable melanoma metastases. To determine the effects of disrupting a nodal basin in patients with American Joint Committee on Cancer stage III melanoma with clinically palpable lymph nodes, we studied patients who underwent therapeutic lymph node dissection after excisio…
TOPOLOGY
CORRELATIONS
W – Weight-space · similarity between decoder vectors (features that point in similar directions in the embedding space).
D – Data / co-activation · features that tend to fire together on the same documents (co-occurrence in the dataset).